In order to study the variation of complex impedance and characteristic parameters on human normal and tumor lung tissue during the extracorporeal time, we established a real part-imaginary part chart of complex impedance on lung tissue which provided the basic theory and the reference data for research on elementary medicine and clinical diagnosis of lung cancer and meanwhile provided prior information for electrical impedance tomography (EIT) research. In the experiment carried out in our laboratory, when operation was finished, we kept the lung cancer tissue and normal tissue neatly separated into the cylindrical testing cavities and kept the temperature and humidity at expected values. Then the measurements of complex impedance property are performed at frequency from 1 000 Hz to 30 MHz using 4294A impedance analyzer of Aglient Company. With time changing, the results showed that there was a significant change occurring on the complex impedance of human normal and tumor lung tissue. However, the impedance of normal lung tissue is greater than that of tumor lung tissue. We consider that this change should be related to the change in extracellular fluid, intracellular fluid and cell membrane.
Citation：
PANGShan, WANGHuaxiang, XUXiao. Study on Complex Impedance Properties of Human Lung Tissue. Journal of Biomedical Engineering, 2014, 31(3): 527-531. doi: 10.7507/1001-5515.20140098
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Copyright © the editorial department of Journal of Biomedical Engineering of West China Medical Publisher. All rights reserved
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- 2. SICONOLFI S F, GRETEBECK R J, WONG W W, et al. Assessing total body and extracellular water from bioelectrical response spectroscopy[J]. J Appl Physiol, 1997, 82(2):704-710.
- 3. BRAMLETT H M, DIETRICH W D. Progressive damage after brain and spinal cord injury:pathomechanisms and treatment strategies[J]. Prog Brain Res, 2007, 161(1):125-141.
- 4. PIACENTINI R, RIPOLI C, MEZZOGORI D, et al. Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Ca(v)1-channel activity[J]. J Cell Physiol, 2008, 215(1):129-139.
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