Integrated Development of Full-automatic Fluorescence Analyzer_Journal of Biomedical Engineering

Authors：

 ZHANGMei ^1,2 , LINZhibo ^1,2 , YUANPeng ^1,2 , YAOZhifeng ^1,2 , HUYueming ^1,2

1. Engineering Research Center for Precision Electronic Manufacturing Equipments of Ministry of Education, Guangzhou 510640, China;
2. College of Automation Science and Engineering, South China University of Technology, Guangzhou 510640, China;

Corresponding author：

ZHANGMei, Email: zhangmei@scut.edu.cn

Keywords：

immunoassay; full-automatic fluorescence analyzer; C#; motion control

DOI：

10.7507/1001-5515.20150198

Video：

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In view of the fact that medical inspection equipment sold in the domestic market is mainly imported from abroad and very expensive, we developed a full-automatic fluorescence analyzer in our center, presented in this paper. The present paper introduces the hardware architecture design of FPGA/DSP motion controlling card+PC+STM32 embedded micro processing unit, software system based on C# multi thread, design and implementation of double-unit communication in detail. By simplifying the hardware structure, selecting hardware legitimately and adopting control system software to object-oriented technology, we have improved the precision and velocity of the control system significantly. Finally, the performance test showed that the control system could meet the needs of automated fluorescence analyzer on the functionality, performance and cost.

Citation： ZHANGMei, LINZhibo, YUANPeng, YAOZhifeng, HUYueming. Integrated Development of Full-automatic Fluorescence Analyzer. Journal of Biomedical Engineering, 2015, 32(5): 1118-1124. doi: 10.7507/1001-5515.20150198 Copy

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1. 李冬,杨新华,王树杰.自动化生化分析仪国内外现状及进展[J].现代仪器,2006,12(1):4-8.
2. 祝连庆,张文昌,董明利,等.一种提高全自动酶免分析仪微量移液精度的方法[J].仪器仪表学报,2013,34(5):1008-1014.
3. 王晛,陈剑虹,杨佳丽,等.基于模糊PID控制的InGaAs光电探测器的温控系统[J].计算机测量与控制,2012,6:1518-1520,1526.
4. ROBISON W, 邱仲潘.C#开发人员手册[J].2000.
5. 贾广雷,刘培玉,耿长欣.多线程技术及其在串口通信中的应用[J].计算机科学,2002,29(8):148-149,130.
6. 朱建国,李科杰,高峻峣,等.煤矿探测与救援机器人分布式控制系统设计[J].计算机测量与控制,2011,19(11):2686-2688,2707.
7. LEE J H, KIM J K, KIM H S, et al. Development of multi-axis gantry type welding robot system using a PC-based controller[C]//IEEE International Symposium on Industrial Electronics, 2001. 2001, 3:1536-1541.
8. 周亚军,张毅,张玉娇,李盛强,等.多轴电火花加工(EDM)数控系统的设计[J].仪器仪表学报,2007,28(9):1712-1717.
9. SCEPPA D. ADO.NET技术内幕[M].北京:清华大学出版社,2003.
10. 封洲燕,郑筱祥.采样参数变化对脑电信号复杂度分析的影响[J].生物医学工程学杂志,2002,19(4):616-620.

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Integrated Development of Full-automatic Fluorescence Analyzer

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