Objective To review the current research status of in situ three-dimensional (3-D) printing technique and future trends.
Methods Recent related literature about in situ 3-D printing technique was summarized, reviewed, and analyzed.
Results Based on the cl inical need for surgical repair, in situ 3-D printing technique is in the preliminary study, mainly focuses on in situ dermal repair and bone and cartilage repair, and succeeds in experiments, but there are still a lot of problems for cl inical application.
Conclusion With the development of in situ 3-D printing technique, it will provide patients with real-time and in situ digital design and 3-D printing treatment with a timely and minimally invasive surgical repair process. It will be widely used in the future.
Citation：
CHENDong, LIUYaxiong, HEJiankang, WANGZhen, MALei, JINZhongmin. RESEARCH STATUS AND FUTURE OF IN SITU THREE-DIMENSIONAL PRINTING TECHNIQUE. Chinese Journal of Reparative and Reconstructive Surgery, 2014, 28(11): 1428-1430. doi: 10.7507/1002-1892.20140307
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Copyright © the editorial department of Chinese Journal of Reparative and Reconstructive Surgery of West China Medical Publisher. All rights reserved
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胡大海, 王洪涛, 王耘川, 等.组织工程皮肤研究现状.创伤与急危重病医学, 2013, 1(1):13-16, 24.
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Binder KW, Zhao W, Aboushwareb T, et al. In situ bioprinting of the skin for burns. Journal of the American College of Surgeons, 2010, 211(3):7.
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Microfab. 3-D Printing[EB/OL].[2014-03-26] http://www.microfab.com/index.php?option=com_content&view=article&id=116&Itemid=158.
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Sofokleous P, Stride E, Bonfield W, et al. Design, construction and performance of a portable handheld electrohydrodynamic multi-needle spray gun for biomedical applications. Materials Science and Engineering: C, 2013, 33(1):213-223.
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康苗侠.急性颅脑损伤病人的术后护理.全科护理, 2010, 8(4期下旬版):1095-1096.
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赵培荣.重型颅脑损伤病人的呼吸道护理.护理研究, 2009, 23(S2): 81.
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Keriquel V, Guillemot F, Arnault I, et al. In vivo bioprinting for computer-and robotic-assisted medical intervention:preliminary study in mice. Biofabrication, 2010, 2(1):014101.
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Cohen DL, Lipton JI, Bonassar LJ, et al. Additive manufacturing for in situ repair of osteochondral defects. Biofabrication, 2010, 2(3):035004.
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Alyn Griffiths. 3D-printing Biopen "draws" with l iving cells to repair damaged bones[EB/OL]. (2013-12-23)[2014-3-26] http://www.dezeen.com/2013/12/23/3d-printing-biopen-draws-bone-repairswith-stem-cells/.
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清华大学医学院.刘静小组提出植入式医疗电子生物体内3D打印成型技术[EB/OL].[2014-3-26] http://www.med.singhua.edu.cn/index.php/zh/about-us/latest-news/366-3d.
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Jin C, Zhang J, Li XK, et al. Injectable 3-D fabrication of medical electronics at the target biological tissues. Scientific Reports, 2013, 3:3442.
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Takebe T, Sekine K, Enomura M, et al. Vascularized and functional human l iver from an iPSC-derived organ bud transplant. Nature, 2013, 499(7459):481-484.
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- 1. 胡大海, 王洪涛, 王耘川, 等.组织工程皮肤研究现状.创伤与急危重病医学, 2013, 1(1):13-16, 24.
- 2. Binder KW, Zhao W, Aboushwareb T, et al. In situ bioprinting of the skin for burns. Journal of the American College of Surgeons, 2010, 211(3):7.
- 3. Microfab. 3-D Printing[EB/OL].[2014-03-26] http://www.microfab.com/index.php?option=com_content&view=article&id=116&Itemid=158.
- 4. Sofokleous P, Stride E, Bonfield W, et al. Design, construction and performance of a portable handheld electrohydrodynamic multi-needle spray gun for biomedical applications. Materials Science and Engineering: C, 2013, 33(1):213-223.
- 5. 康苗侠.急性颅脑损伤病人的术后护理.全科护理, 2010, 8(4期下旬版):1095-1096.
- 6. 赵培荣.重型颅脑损伤病人的呼吸道护理.护理研究, 2009, 23(S2): 81.
- 7. Keriquel V, Guillemot F, Arnault I, et al. In vivo bioprinting for computer-and robotic-assisted medical intervention:preliminary study in mice. Biofabrication, 2010, 2(1):014101.
- 8. Cohen DL, Lipton JI, Bonassar LJ, et al. Additive manufacturing for in situ repair of osteochondral defects. Biofabrication, 2010, 2(3):035004.
- 9. Alyn Griffiths. 3D-printing Biopen "draws" with l iving cells to repair damaged bones[EB/OL]. (2013-12-23)[2014-3-26] http://www.dezeen.com/2013/12/23/3d-printing-biopen-draws-bone-repairswith-stem-cells/.
- 10. 清华大学医学院.刘静小组提出植入式医疗电子生物体内3D打印成型技术[EB/OL].[2014-3-26] http://www.med.singhua.edu.cn/index.php/zh/about-us/latest-news/366-3d.
- 11. Jin C, Zhang J, Li XK, et al. Injectable 3-D fabrication of medical electronics at the target biological tissues. Scientific Reports, 2013, 3:3442.
- 12. Takebe T, Sekine K, Enomura M, et al. Vascularized and functional human l iver from an iPSC-derived organ bud transplant. Nature, 2013, 499(7459):481-484.
