Objective To evaluate the effect of dilute autotransfusion in liver resection for patients with hepatic hydatid disease.
Method Thirty patients with hepatic hydatid disease met the inclusion criteria were included. The changes of intraoperative hemodynamics, internal environment, and each system functions at different time point were observed.
Results ①There were no significant differences among mean arterial pressure, central venous pressure, heart rate in all the patients at each time point (P > 0.05), while, the other indexes including the concentrations of hemoglobin (Hb), hematocrit (Hct) after blood collection were all greatly lower than those before blood collection (P < 0.05), Na+, K+, Cl-, pH, and base excess after blood collection were all greatly lower than those before blood collection (P < 0.05). But all the indexes above mentioned (except for ph and base excess) returned to normal.②Compared with these indicators before surgery, the blood concentrations of AST, ALT, cardiac troponin I, and creatinin were all greatly increased (P < 0.05), the blood concentrations of Hb, Hct, platelet were all decreased apparently after surgery 1 day (P < 0.05). The prothrombin time and activated partial thromboplastin time were all prolonged (P < 0.05). But after surgery one week, those indicators had rebounded to the normal range.
Conclusion The application of dilute autotransfusion in liver surgery for patients with hepatic hydatid disease is safe, feasible, and saving.
Citation：
LUOXiao-qin, YANGKang-ming, ZHANGTan, LIUQing, GESang-qu-zhen, YANGXue-mei, ZOUGuo-ling, LUOYan, LIXin-mei, JIANGChao-pin, CHENZhe-yu. Clinical Application of Hemodilution Autotransfusion in Liver Resection for Patients with Hepatic Echinococcosis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(2): 154-158. doi: 10.7507/1007-9424.20150042
Copy
Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
| 1. |
梁兵, 田兆嵩.稀释式自身输血.中国输血杂志, 2005, 18(6): 520-524.
|
| 2. |
李长龙, 景鸿恩.肝包虫病的诊断与治疗现状.中外医学研究, 2012, 10(5): 158-160.
|
| 3. |
温浩.肝包虫病诊断和手术治疗新进展.中华消化外科杂志, 2011, 10(4): 290-292.
|
| 4. |
邬露丹, 徐炜峰, 郭建荣, 等.急性等容血液稀释对老年肝切除术患者血浆蛋白、凝血功能的影响.现代实用医学, 2008, 20(2): 86-87, 91.
|
| 5. |
陶红斌, 黄焕娟, 詹鸿, 等.回收式自体输血联合血液稀释应用于骨科手术的研究.热带医学杂志, 2010, 3(3): 333.
|
| 6. |
林健清, 林财珠, 杨庆.急性等容性血液稀释对肝脏手术纤维蛋白降解产物D-二聚体和凝血功能的影响.临床麻醉学杂志, 2006, 22(5): 324-326.
|
| 7. |
夏晓峰, 钱宝华.术中回收式自身输血的研究进展.中国输血杂志, 2008, 21(4): 310-314.
|
| 8. |
Valter C, Giovanni S, Da CR, et al. Intraoperative low-volume acute normovolemic hemodilution in adult open-heart surgery. Anesthesiology, 2002, 97(2): 367-373.
|
| 9. |
谭丽莉, 王海燕, 张树超, 等.急性等容稀释性自身输血在心脏外科手术中的应用.中国输血杂志, 2009, 22(10): 820-821.
|
| 10. |
Bennett J, Haynes S, Torella F, et al. Acute normovolemic hemodilution in moderate blood loss surgery: a randomized controlled trial. Transfusion, 2006, 46(7): 1097-1103.
|
| 11. |
徐彬.血液稀释研究的若干进展.内蒙古中医药, 2013, 32(18): 155-156.
|
| 12. |
赵桂军, 孙莉, 邵永孚.急性等容血液稀释自身输血应用于腹部肿瘤患者手术的可行性.中华医学杂志, 2003, 83(11): 1000-1001.
|
| 13. |
Matot I, Scheinin O, Jurim O, et al. Effectiveness of acute normovolemic hemodilution to minimize allogeneic blood transfusion in major liver resections. Anesthesiology, 2002, 97(4): 794-800.
|
| 14. |
Guo JR, Jin XJ, Yu J, et al. Acute normovolemic hemodilution effects on perioperative coagulation and fibrinolysis in elderly patients undergoing hepatic carcinectomy. Chin Med Sci, 2010, 25(3): 146-150.
|
| 15. |
Saricaoglu F, Akinci SB, Celiker V, et al. The effect of acute normovolemic hemodilution and acute hypervolemic hemodilution on coagulation and allogeneic transfusion. Saudi Med J, 2005, 26(5): 792-798.
|
- 1. 梁兵, 田兆嵩.稀释式自身输血.中国输血杂志, 2005, 18(6): 520-524.
- 2. 李长龙, 景鸿恩.肝包虫病的诊断与治疗现状.中外医学研究, 2012, 10(5): 158-160.
- 3. 温浩.肝包虫病诊断和手术治疗新进展.中华消化外科杂志, 2011, 10(4): 290-292.
- 4. 邬露丹, 徐炜峰, 郭建荣, 等.急性等容血液稀释对老年肝切除术患者血浆蛋白、凝血功能的影响.现代实用医学, 2008, 20(2): 86-87, 91.
- 5. 陶红斌, 黄焕娟, 詹鸿, 等.回收式自体输血联合血液稀释应用于骨科手术的研究.热带医学杂志, 2010, 3(3): 333.
- 6. 林健清, 林财珠, 杨庆.急性等容性血液稀释对肝脏手术纤维蛋白降解产物D-二聚体和凝血功能的影响.临床麻醉学杂志, 2006, 22(5): 324-326.
- 7. 夏晓峰, 钱宝华.术中回收式自身输血的研究进展.中国输血杂志, 2008, 21(4): 310-314.
- 8. Valter C, Giovanni S, Da CR, et al. Intraoperative low-volume acute normovolemic hemodilution in adult open-heart surgery. Anesthesiology, 2002, 97(2): 367-373.
- 9. 谭丽莉, 王海燕, 张树超, 等.急性等容稀释性自身输血在心脏外科手术中的应用.中国输血杂志, 2009, 22(10): 820-821.
- 10. Bennett J, Haynes S, Torella F, et al. Acute normovolemic hemodilution in moderate blood loss surgery: a randomized controlled trial. Transfusion, 2006, 46(7): 1097-1103.
- 11. 徐彬.血液稀释研究的若干进展.内蒙古中医药, 2013, 32(18): 155-156.
- 12. 赵桂军, 孙莉, 邵永孚.急性等容血液稀释自身输血应用于腹部肿瘤患者手术的可行性.中华医学杂志, 2003, 83(11): 1000-1001.
- 13. Matot I, Scheinin O, Jurim O, et al. Effectiveness of acute normovolemic hemodilution to minimize allogeneic blood transfusion in major liver resections. Anesthesiology, 2002, 97(4): 794-800.
- 14. Guo JR, Jin XJ, Yu J, et al. Acute normovolemic hemodilution effects on perioperative coagulation and fibrinolysis in elderly patients undergoing hepatic carcinectomy. Chin Med Sci, 2010, 25(3): 146-150.
- 15. Saricaoglu F, Akinci SB, Celiker V, et al. The effect of acute normovolemic hemodilution and acute hypervolemic hemodilution on coagulation and allogeneic transfusion. Saudi Med J, 2005, 26(5): 792-798.
