YueWeigang , ZhangZhigang , MaFangli , LiBin
  • Intensive Care Unit, The First Hospital of Lanzhou University, Lanzhou, Gansu, 730000, China;
YueWeigang, Email: yueweigang5963@163.com
CoughAssist; Nerve-muscle disease; Respiratory secretions cleanup; Respiratory infections
10.7507/1671-6205.2014143
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Objective To investigate the clinical efficacy of CoughAssist for cleaning airway secretions in neuromuscular disease patients with respiratory insufficiency. Methods Forty-six cases of neuromuscular disease with respiratory insufficiency were recruited in the study,with Guillain-Barre syndrome in 24 cases,myasthenia gravis in 18 cases,and multiple myositis in 4 patients.Thirty-four patients underwent intubation and mechanical ventilation,and 12 patients underwent tracheotomy.They were randomly divided into group A using CoughAssist and group B using suction tube to clear airway secretions after mechanical vibration.The frequency of suction within 24 hours,oxygenation index,pulmonary static compliance,incidence of lung infections,lung auscultation and chest radiograph were recorded and compared between two groups. Results CoughAssist could more effectively clean respiratory secretions with higher oxygenation index and pulmonary static compliance in group A.Lung auscultation and chest radiograph significantly improved,and the incidence of lung infection significantly decreased in group A compared with group B.Furthermore,CoughAssist reduced nursing workload with lower frequency of suction within 24 hours. Conclusion CoughAssist can effectively clean up airway secretions,improve oxygenation,while reducing pulmonary infection and nursing workload for neuromuscular disease patients with respiratory insufficiency,so it is aworthy tool in clincal practice.

Citation： YueWeigang, ZhangZhigang, MaFangli, LiBin. Clinical Efficacy of CoughAssist for Cleaning Airway Secretions in Neuromuscular Disease Patients with Respiratory Insufficiency. Chinese Journal of Respiratory and Critical Care Medicine, 2014, 13(6): 588-590. doi: 10.7507/1671-6205.2014143 Copy

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