Clinical Analysis of Infants in 402 Cases with Melamine-Induced Urolithiasis in Gansu Province_Chinese Journal of Evidence-Based Medicine

Authors：

LIGuangjie, YUE Zhongjin, YANG Kehu, TIAN Junqiang, SHANG Panfeng, BAO Junsheng, LU Jianzhong, WANG Wei

1. Department of Urology, the Second Hospital of LanZhou University,LanZhou 730030, China;2. Evidence-Based Medicine Center of Lanzhou University, Lanzhou 730000, China;3. Institute of Urology, the Second Hospital of LanZhou University, LanZhou 730030, China;

Corresponding author：

Keywords：

Melamine; Infant; Urolithiasis; Obstructive renal failure; Gansu province

DOI：

10.7507/1672-2531.20100061

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective 　To discuss the prevalence of melamine-induced urolithiasis in infants and its development and to formulate more effective diagnosis and treatment.
Methods 　A total of 402 cases of melamine-induced infantile urolithiasis were retrospectively analyzed with basic information, blood, urine, urinary B-mode ultrasonic diagnosis, treatment options and prognosis for infant urolithiasis.
Results 　A total of 402 cases of infants had an excessive melamine milk feeding history, in which there were 9 self-discharged cases. The largest calculus diameter was 4 mm × 5 mm × 6 mm. The smallest calculus diameter was 0.5 mm × 0.5 mm × 1 mm. The average calculus diameter was 1 mm × 2 mm × 2 mm. There were 30 cases of abnormal serum creatinine, 27 of abnormal urea, 2 of abnormal uric acid, and urine occult blood positive for 167 cases. There were 395 cases which were administrated medical treatment; 7 cases were administrated surgical treatment; 6 cases had obstructive renal failure.
Conclusion 　Infants whose age is more than six months but less than 12 months with a history of exposure to melamine have the larger risk of urolithiasis. B-mode ultrasonic diagnosis is practically significant on early screening urolithiasis. It is effective to perform surgical treatment for obstructive renal failure caused by calculus.

Citation： LI Guangjie,YUE Zhongjin,YANG Kehu,TIAN Junqiang,SHANG Panfeng,BAO Junsheng,LU Jianzhong,WANG Wei. Clinical Analysis of Infants in 402 Cases with Melamine-Induced Urolithiasis in Gansu Province. Chinese Journal of Evidence-Based Medicine, 2010, 10(1): 23-25. doi: 10.7507/1672-2531.20100061 Copy

1.	蒋也平, 樊剑锋, 周楠, 等. 三聚氰胺致婴幼儿泌尿系结石的治疗与预后. 中国社区医师, 2008, 24(20): 12.
2.	胡世莲, 吴蕾, 陈尹. 安徽中部地区食用含三聚氰胺超标奶粉婴幼儿泌尿系统结石发病情况调查. 中国循证医学杂志, 2008, 8(12): 1039-1042.
3.	孙西钊. 问题奶粉致尿路结石形成机制初探及诊治建议. 临床泌尿外科杂志, 2008, 23(11): 805-809.
4.	Ho SS, Chu WC, Wong KT, et al. Ultrasonographic evaluation of melamine-exposed children in Hong Kong. N Engl J Med, 2009, 360(11): 1156-1157.
5.	周楠, 张克玲. 三聚氰胺致婴幼儿泌尿系结石致急性肾衰竭的治疗. 中国社区医师, 2008, 24(20): 13.
6.	廖承琳, 潘家骅, 吕勇, 等. 问题奶粉导致小儿泌尿系统结石的诊疗策略. 安徽医学, 2008, 29(6): 676-677.
7.	Langman CB, Alon U, Ingelfinger J, et al. A position statement on kidney disease from powdered infant formula-based melamine exposure in Chinese infants. Pediatr Nephrol, 2009, 7. [Epub ahead of print].

1. 蒋也平, 樊剑锋, 周楠, 等. 三聚氰胺致婴幼儿泌尿系结石的治疗与预后. 中国社区医师, 2008, 24(20): 12.
2. 胡世莲, 吴蕾, 陈尹. 安徽中部地区食用含三聚氰胺超标奶粉婴幼儿泌尿系统结石发病情况调查. 中国循证医学杂志, 2008, 8(12): 1039-1042.
3. 孙西钊. 问题奶粉致尿路结石形成机制初探及诊治建议. 临床泌尿外科杂志, 2008, 23(11): 805-809.
4. Ho SS, Chu WC, Wong KT, et al. Ultrasonographic evaluation of melamine-exposed children in Hong Kong. N Engl J Med, 2009, 360(11): 1156-1157.
5. 周楠, 张克玲. 三聚氰胺致婴幼儿泌尿系结石致急性肾衰竭的治疗. 中国社区医师, 2008, 24(20): 13.
6. 廖承琳, 潘家骅, 吕勇, 等. 问题奶粉导致小儿泌尿系统结石的诊疗策略. 安徽医学, 2008, 29(6): 676-677.
7. Langman CB, Alon U, Ingelfinger J, et al. A position statement on kidney disease from powdered infant formula-based melamine exposure in Chinese infants. Pediatr Nephrol, 2009, 7. [Epub ahead of print].

Chinese Journal of Evidence-Based Medicine

Clinical Analysis of Infants in 402 Cases with Melamine-Induced Urolithiasis in Gansu Province

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content