Objective To compare the outpatient in gynecology department with health screening women in aspects of general condition, bearing, livelihood, economics and family, and to analyze the factors that relate to premature ovarian failure (POF) and diminished ovarian reserve (DOR).
Method To survey 178 outpatients of gynecology department and health screening women visited from January to December of 2007, and to investigate the possible related factors through a questionnaire including the condition of basic information (e.g. age, marital status, occupation and education), menstruation, pregnancy and delivery, contraception, health, livelihood, economics, psychology, society, family and so on. The data were analyzed with SPSS 13.0 software.
Results A total of 45 POF patients, 83 DOR patients and 50 healthy women were included. The results of questionnaire showed that the physiological factor was the main reason for the occurrence of POF and DOR; the menstrual disorders, autoimmune diseases (such as systemic lupus erythematosus, idiopathic thrombocytopenic purpura, glomerulonephritis, rheumatoid arthritis, etc.), malignancy cancer, pelvic surgery, smoking and drug abuse, and lack of sleep were closely related to POF and DOR; the social and psychological factors were other main reasons to cause POF and DOR.
Conclusion The onset of both POF and DOR is caused by many factors, such as physical, social and psychological factors. The effective prevention and treatment for these diseases should be conducted positively in accordance with these three aspects.
Citation:
XU Xiaofeng,FAN Chun,BAO Guangqin,CHEN Xiuling,GU Ying. Investigation on the Factors Related to Premature Ovarian Failure and Diminished Ovarian Reserve. Chinese Journal of Evidence-Based Medicine, 2011, 11(4): 400-403. doi: 10.7507/1672-2531.20110070
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Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
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艾浩, 牛建昭, 薛晓鸥, 等. 化疗损伤性卵巢功能早衰小鼠动物模型的研究. 中国实验动物学报, 2007, 15(1): 35-38.
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邓姗, 冷金花, 郎景和, 等. 腹腔镜下卵巢子宫内膜异位囊肿剔除术相关并发症分析. 中国实用妇科与产科杂志, 2007, 23(8): 622-624.
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季慧玲, 邵敬於. 卵巢保守性手术后卵巢早衰临床分析. 现代妇产科进展, 2001, 10(4): 261-263.
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庞震苗, 易颖, 陈凯佳. 卵巢早衰发病的流行病学调查及可能性预测的数学模型的构建. 现代中西医结合杂志, 2007, 16(28): 4257-4258.
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谷红霞, 李芹, 孙丰娥. 卵巢早衰患者的心理护理. 齐鲁护理杂志, 2008, 14(15): 92-92.
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王丽, 任春娥, 姜爱芳, 等. 卵巢早衰患者的心理状态分析及护理. 潍坊医学院学报, 2008, 30(1): 1004-1011.
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杨秀坤, 杨秀燕, 马良坤. 卵巢早衰的防治对策. 中国妇幼保健, 2003, 18(11): 699.
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曹立英, 王海彦. 卵巢早衰的综合治疗. 中国实用医药, 2009, 4(15): 72-73.
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- 1. 7 Monnier-Barbarino P, Forges T, Faure GC,
et al . Gonadal antibodies interfering with female reproduction. Best Pract Res Clin Endocrinol Metab , 2005, 19(1): 135-148.
- 2. 陈静, 阮祥燕. 卵巢早衰研究进展. 医学综述, 2010, 16(18): 2727-2729.
- 3. 金志春. 卵巢早衰对女性性功能的影响及其防治. 中华实用中西医杂志, 2008, 21(16): 1318-1320.
- 4. 中华医学会编著. 临床诊疗指南(妇产科学分册). 北京: 人民卫生出版社, 2007: 118.
- 5. 金婧. 卵巢早衰的病因研究进展. 实用妇产科杂志, 2007, 23(3): 142-145.
- 6. Aleksandar Rajkovic. Genetics of Premature Ovarian Failure (insufficiency). 2010年国际生殖内分泌和生殖遗传研讨会论文汇编. 2010: 24-32.
- 7. 马小红, 徐仙. 卵巢早衰与自身免疫机制的研究进展. 中国计划生育学杂志, 2007, 137(3): 186-188.
- 8. 艾浩, 牛建昭, 薛晓鸥, 等. 化疗损伤性卵巢功能早衰小鼠动物模型的研究. 中国实验动物学报, 2007, 15(1): 35-38.
- 9. 王桂玲, 任春娥. 化疗引发的卵巢早衰防治研究进展. 河北医药, 2008, 30(4): 528-530.
- 10. 邓姗, 冷金花, 郎景和, 等. 腹腔镜下卵巢子宫内膜异位囊肿剔除术相关并发症分析. 中国实用妇科与产科杂志, 2007, 23(8): 622-624.
- 11. 季慧玲, 邵敬於. 卵巢保守性手术后卵巢早衰临床分析. 现代妇产科进展, 2001, 10(4): 261-263.
- 12. 庞震苗, 易颖, 陈凯佳. 卵巢早衰发病的流行病学调查及可能性预测的数学模型的构建. 现代中西医结合杂志, 2007, 16(28): 4257-4258.
- 13. 谷红霞, 李芹, 孙丰娥. 卵巢早衰患者的心理护理. 齐鲁护理杂志, 2008, 14(15): 92-92.
- 14. 王丽, 任春娥, 姜爱芳, 等. 卵巢早衰患者的心理状态分析及护理. 潍坊医学院学报, 2008, 30(1): 1004-1011.
- 15. 杨秀坤, 杨秀燕, 马良坤. 卵巢早衰的防治对策. 中国妇幼保健, 2003, 18(11): 699.
- 16. 曹立英, 王海彦. 卵巢早衰的综合治疗. 中国实用医药, 2009, 4(15): 72-73.