Objective To explore the correlation between hematocrit and slow coronary flow (SCF) in male patients.
Methods We studied 205 patients with angiographically no more than one stenosis lt;40% in each major coronary artery who had admitted to the department of cardiology of the Beijing Anzhen Hospital Affiliated to Capital Medical University from August 2011 to August 2012. According to the level of hematocrit, 101 patients were classified into the trial group whose hematocrit was more 42.9%, while 104 patients into the control group whose hematocrit was no more than 42.9%. Clinical variables were analyzed and compared between the two groups.
Results The age was younger in the trial group than the control group, whereas the levels of white blood cell count, mean platelet volume, triglyceride, low-density lipoprotein cholesterol, left anterior descending artery (LAD) and right coronary artery (RCA) TIMI frame count and the proportion of SCF in the LAD were higher in the trial group than in the control group (P lt;0.05). The results of correlation analysis showed that, LAD TIMI frame count (r=0.238, P=0.001), proportion of SCF in the LAD (r=0.206, P=0.003) and RCA TIMI frame count (r=0.209, P=0.003) were positively correlated with hematocrit. The results of multivariate analysis (using logistic regression with adjusted confounding factors such as age) showed that, LAD TIMI frame count (OR=1.031, 95%CI 1.006 to 1.056, P=0.014), proportion of SCF in the LAD (OR=1.919, 95%CI 1.038 to 3.547, P=0.038) were independently correlated with hematocrit.
Conclusion The proportion of SCF in the LAD is independently correlated to hematocrit, which suggested that increased hematocrit may contribute to the pathophysiological change of SCF in male patients.
Citation：
WANG Su,SUN Tao,ZHANG Yanyan,CHENG Yutong,YIN Chengqian,ZHANG Donghua,LIU Tong,ZHANG Jingmei,LI Zhizhong. Correlation between Hematocrit and Slow Coronary Flow in Male Patients. Chinese Journal of Evidence-Based Medicine, 2013, 13(10): 1172-1175. doi: 10.7507/1672-2531.20130200
Copy
Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
| 1. |
王苏, 周玉杰. 冠状动脉慢血流研究进展. 中华实用诊断与治疗杂志, 2013, 25(5): 421-423.
|
| 2. |
Endres HG, Wedding U, Pittrow D, et al. Prevalence of anemia in elderly patients in primary care: impact on 5-year mortality risk and differences between men and women. Curr Med Res Opin, 2009, 25(5): 1143-1158.
|
| 3. |
van Straten AH, Hamad MA, van Zundert AJ, et al. Preoperative hemoglobin level as a predictor of survival after coronary artery bypass grafting: a comparison with the matched general population. Circulation, 2009, 120(2): 118-125.
|
| 4. |
Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation, 1996, 93(5): 879-888.
|
| 5. |
Ergun-Cagli K, Ileri-Gurel E, Ozeke O, et al. Blood viscosity changes in slow coronary flow patients. Clin Hemorheol and Microcirc, 2011,47 (1): 27-35.
|
| 6. |
Bilgi M, Güllü H, Kozanoğlu İ, et al. Evaluation of blood rheology in patients with coronary slow flow or non-obstructive coronary artery disease. Clin Hemorheol and Microcirc, 2013, 53(4): 317-326.
|
| 7. |
王苏, 孙涛, 孙俊平, 等. 冠状动脉慢血流现象影响因素研究. 中华实用诊断与治疗杂志, 2012, 26(11): 1048-1050.
|
| 8. |
Salazar Vázquez BY, Martini J, Chávez Negrete A, et al. Cardiovascular benefits in moderate increases of blood and plasma viscosity surpass those associated with lowering viscosity: Experimental and clinical evidence. Clin Hemorheol Microcirc, 2010, 44 (2):75-85.
|
| 9. |
Salazar Vázquez BY, Cabrales P, Tsai AG, et al. Nonlinear cardiovascular regulation consequent to changes in blood viscosity. Clin Hemorheol Microcirc, 2011, 49(1-4): 29-36.
|
- 1. 王苏, 周玉杰. 冠状动脉慢血流研究进展. 中华实用诊断与治疗杂志, 2013, 25(5): 421-423.
- 2. Endres HG, Wedding U, Pittrow D, et al. Prevalence of anemia in elderly patients in primary care: impact on 5-year mortality risk and differences between men and women. Curr Med Res Opin, 2009, 25(5): 1143-1158.
- 3. van Straten AH, Hamad MA, van Zundert AJ, et al. Preoperative hemoglobin level as a predictor of survival after coronary artery bypass grafting: a comparison with the matched general population. Circulation, 2009, 120(2): 118-125.
- 4. Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation, 1996, 93(5): 879-888.
- 5. Ergun-Cagli K, Ileri-Gurel E, Ozeke O, et al. Blood viscosity changes in slow coronary flow patients. Clin Hemorheol and Microcirc, 2011,47 (1): 27-35.
- 6. Bilgi M, Güllü H, Kozanoğlu İ, et al. Evaluation of blood rheology in patients with coronary slow flow or non-obstructive coronary artery disease. Clin Hemorheol and Microcirc, 2013, 53(4): 317-326.
- 7. 王苏, 孙涛, 孙俊平, 等. 冠状动脉慢血流现象影响因素研究. 中华实用诊断与治疗杂志, 2012, 26(11): 1048-1050.
- 8. Salazar Vázquez BY, Martini J, Chávez Negrete A, et al. Cardiovascular benefits in moderate increases of blood and plasma viscosity surpass those associated with lowering viscosity: Experimental and clinical evidence. Clin Hemorheol Microcirc, 2010, 44 (2):75-85.
- 9. Salazar Vázquez BY, Cabrales P, Tsai AG, et al. Nonlinear cardiovascular regulation consequent to changes in blood viscosity. Clin Hemorheol Microcirc, 2011, 49(1-4): 29-36.
