TIAN Xu 1,2 # , LIU Xiaoling 1 # , CHEN Hui 1 , PI Yuanping 3 , CHEN Weiqing 1
  • 1. Key Laboratory for Biorheological Science and Technology of Ministry of Education (Chongqing University), Chongqing Cancer Institute & Chongqing Cancer Hospitol, Chongqing University Cancer Hospital, Chongqing, 400044, P.R.China;
  • 2. Editorial Office, TMR Integrative Nursing, TMR Publishing Group, Tianjin, 300210, P.R.China;
  • 3. Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing University Cancer Hospital, Chongqing, 400030, P.R.China;
CHEN Weiqing, Email: chenwq20140809@163.com
Lidocaine; Dyclonine; Gastroscopy; Preoperative preparation; Meta-analysis; Systematic review; Randomized controlled trial
10.7507/1672-2531.201801024
Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables References Cited by

ObjectivesTo systematically review the efficacy of dyclonine and lidocaine for preparation before gastroscopy.MethodsPubMed, CNKI, CBM, VIP and WanFang Data databases were electronically searched to collect randomized controlled trials (RCTs) of dyclonine vs. lidocaine for preparation before gastroscopy from inception to December 31st, 2017. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Meta-analysis was then performed by using RevMan 5.3 software.ResultsA total of 11 RCTs were included. The results of meta-analysis showed that: dyclonine could improve anesthetic effect (RR=1.38, 95%CI 1.31 to 1.47, P<0.000 01), and was more capable to remove bubble (RR=1.40, 95%CI 1.28 to 1.52,P<0.000 01), and had superior textures (RR=1.43, 95%CI 1.18 to 1.74,P=0.000 3).ConclusionsOral dyclonine can improve the visual definition of gastric mucosa and anesthetic effect, and has superior textures. Thus, dyclonine can be regarded as a recommended option prior to gastroscopy. Due to limited quality and quantity of the included studies, more high quality studies are required to verify above conclusions.

Citation： TIAN Xu, LIU Xiaoling, CHEN Hui, PI Yuanping, CHEN Weiqing. Efficacy of dyclonine and lidocaine for preparation pirior to gastroscopy: a meta-analysis. Chinese Journal of Evidence-Based Medicine, 2018, 18(7): 693-699. doi: 10.7507/1672-2531.201801024 Copy

Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved

  • Previous Article

    Efficacy and safety of autologous bone marrow mesenchymal stem cells transplantation for spinal cord injury: a systematic review WANGQian,  HUANG Guoxin,  ZHANG Huiting,  SHI Ye,  LIU Chufan,  Pradhananga Manish,  AI Jinwei,  PEI Bin

  • Next Article

    Association of homocysteine and contrast-induced nephropathy: a meta-analysis XUEYu,  LI Jingbo,  WANG Lina