Nonrandomized studies are an important method for evaluating the effects of exposures (including environmental, occupational, and behavioral exposures) on human health. Risk of bias in nonrandomized studies of exposures (ROBINS-E) is used to evaluate the risk of bias in natural or occupational exposure observational studies. This paper introduces the main contents of ROBINS-E 2022, including backgrounds, seven domains, signal questions and the operation process.
Citation: WEI Laiwu, CHEN Xiaojing, CAO Yubin, GOU Pan, HUANG Yan, HUA Chengge, LIU Chang. Risk of bias in nonrandomized studies of exposures (ROBINS-E 2022): an interpretation. Chinese Journal of Evidence-Based Medicine, 2023, 23(11): 1340-1350. doi: 10.7507/1672-2531.202302054 Copy
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