LI Yafang 1,2,3 , LIANG Shanshan 1,2,3 , WANG Ziyi 1,2,3 , ZHANG Faqiang 1,2,3 , HUANG Jiayi 1,2,3 , TAO Junliang 1,2,3 , YANG Kehu 1,2,3 , LI Xiuxia 1,2,3
  • 1. Health Technology Evaluation Center/ Evidence-based Social Science Research Center, School of Public Health, Lanzhou University, School of Public Health, Lanzhou University, Lanzhou 730000, P. R. China;
  • 2. Evidence Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, P. R. China;
  • 3. Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou University, Lanzhou 730000, P. R. China;
YANG Kehu, Email: yangkh-ebm@lzu.edu.cn; LI Xiuxia, Email: lixiuxia@lzu.edu.cn
Stroke; Epidemiology; Burden of disease; Systematic review; Meta-analysis
10.7507/1672-2531.202412178
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Objective  To systematically review the incidence, mortality and disease burden of stroke in China. Methods  The CNKI, WanFang Data, VIP, CBM, PubMed, Embase, Web of Science and Cochrane Library databases were electronically searched to collect cohort studies on stroke epidemiology and disease burden from inception to June 30, 2024. Two reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies. Meta-analysis was then performed using Stata 18.0 software. Results  A total of 49 studies were included, and the results showed that the overall incidence of stroke in China was 430/100 000 (95%CI 370/100 000 to 490/100 000); The incidence of stroke in men was 510/100 000 (95%CI 450/100 000 to 580/100 000); The incidence of stroke in women was 370/100 000 (95%CI 320/100 000 to 410/100 000). The overall mortality rate of stroke in China was 220/100 000 (95%CI 160/100 000 to 280/100 000); Stroke mortality in men was 160/100 000 (95%CI 120/100 000 to 190/100 000); Stroke mortality in women was 130/100 000 (95%CI 100/100 000 to 160/100 000). The average standard DALY rate of stroke in China was 2 238.09/100 000, and men (3 510.53/100 000) was higher than that of women (2 083.39/100 000). Conclusion  The risk of stroke in men in China is significantly higher than that in women, which is mainly attributed to the higher rate of smoking and drinking alcohol, poor eating habits and the neglect of health management. Moreover, interregional differences in aging, especially the higher aging levels in the eastern and northern regions, also had a significant impact on stroke incidence in these regions.

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