Objective To evaluate the status of lymph node metastasis and reasonable procedure in gastric cancer.
Methods The incidence of metastases from gastric cancer to various regional lymph node stations was studied in 1 505 patients with gastric cancer. The patients underwent surgical resection from January 1995 to December 2004.
Results Lymph node metastasis were observed in 928 of 1 505 cases (61.7%). Lymph node metastasis frequency was found in groups No.1 (32.9%),No.3 (28.7%), No.2 (20.4%), and No.7 (18.6%) at upper third stomach cancer;in groups No.3 (32.5%), No.4 (24.7%), No.7 (20.6%), and No.1 (17.3%) at middle third stomach cancer; in groups No.6 (33.7%), No.3 (31.3%), No.4 (25.6%), and No.7 (21.5%) at lower third stomach cancer.
Conclusions Distribution of metastatic lymph node is clearly related to the location of the tumor. Anatomical extent of lymph node metastases in gastric cancer provid surgical guidance for surgeons.
Citation:
XU Yan,SUN Zhe,WANG Zhenning,XU Huimian. Primary Study on Anatomical Extent of Lymph Node Metastases in Gastric Cancer and Its Significance in Surgical Treatment. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(1): 16-19. doi:
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1. |
Sobin LH, Wittekind CH, ed. TNM classification of malignant tumours. International Union Against Cancer[M]. 5th edition. New York: John Wiley & Sons, 1997:59-62.
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Deng J, Liang H, Sun D, et al. Suitability of 7th UICC N stage for predicting the overall survival of gastric cancer patients after curative resection in China[J]. Ann Surg Oncol, 2010,17(5):1259-1266.
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陈峻青. 胃癌外科治疗几个问题的新进展[J]. 中国普外基础与临床杂志, 2010, 17(1):1-4.
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Sayegh ME, Sano T, Dexter S, et al. TNM and Japanese staging systems for gastric cancer: how do they coexist?[J]. Gastric Cancer, 2004,7(3):140-148.
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徐岩, 徐惠绵.胃癌转移规律研究新进展[J].中国实用外科杂志, 2011, 31(08):666-669.
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日本胃癌学会編.胃癌取扱い規約(第14版)[M].東京:金原, 2010:5-15.
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Sobin LH, Gospodarowicz MK, Wittekind C. International Union Against Cancer (UICC) TNM classification of malignant tumours[M]. 7th ed. New York:Wiley-Liss, 2010:117-126.
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Noguchi M, Miyazaki I. Prognostic significance and surgical management of lymph node metastasis in gastric cancer[J]. Br J Surg, 1996,83(2):156-161.
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Han KB, Jang YJ, Kim JH, et al. Clinical significance of the pattern of lymph node metastasis depending on the location of gastric cancer[J]. J Gastric Cancer, 2011,11(2):86-93.
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王振宁, 鲁翀, 徐惠绵. 胃上部癌淋巴结转移规律及其在外科治疗中的应用[J].中华实用外科杂志, 2002, 22(10):611-612.
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Tanizawa Y, Terashima M. Lymph node dissection in the resection of gastric cancer:review of existing evidence[J]. Gastric Cancer, 2010,13(3):137-48.
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所剑. 胃癌的淋巴结清扫及意义[J]. 中国普外基础与临床杂志, 2010, 17(1):5-7.
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13. |
Kunisaki C, Shimada H, Nomura M, et al. Distribution of lymph node metastasis in gastric carcinoma[J]. Hepatogastroenterology, 2006,53(69):468-472.
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14. |
Kitamura K, Yamaguchi T, Nishida S, et al. The operative indications for proximal gastrectomy in patients with gastric cancer in the upper third of the stomach[J]. Surg Today, 1997,27(11):993-998.
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Maruyama K, Gunvén P, Okabayashi K, et al. Lymph node metastases of gastric cancer. General pattern in 1 931 patients[J]. Ann Surg, 1989,210(5):596-602.
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16. |
黄宝俊, 鲁翀, 徐莹莹, 等. 292例早期胃癌淋巴结转移规律的研究[J].中华外科杂志, 2007, 45(3): 192-195.
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日本胃癌学会編.胃癌治療ガイドライン(第3版)[M].東京:金原, 2010:12.
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日本胃癌学会編.胃癌取扱い規約(第13版)[M].東京:金原, 2010:7-13.
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Shen DF, Chen DW, Quan ZW, et al. Dissection of No.13 lymph node in radical gastrectomy for gastric carcinoma[J]. World J Gastroenterol,2008,14(6):936-938.
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20. |
朱海涛, 赵宜良, 吴云飞, 等.胃癌各组淋巴结的转移特点及其在实施合理根治术中的指导意义[J]. 中华肿瘤杂志, 2008,30(11):863-865.
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21. |
Tokunaga M, Ohyama S, Hiki N, et al. Therapeutic value of lymph node dissection in advanced gastric cancer with macroscopic duodenum invasion: is the posterior pancreatic head lymph node dissection beneficial?[J]. Ann Surg Oncol, 2009,16(5):1241-1246.
|
- 1. Sobin LH, Wittekind CH, ed. TNM classification of malignant tumours. International Union Against Cancer[M]. 5th edition. New York: John Wiley & Sons, 1997:59-62.
- 2. Deng J, Liang H, Sun D, et al. Suitability of 7th UICC N stage for predicting the overall survival of gastric cancer patients after curative resection in China[J]. Ann Surg Oncol, 2010,17(5):1259-1266.
- 3. 陈峻青. 胃癌外科治疗几个问题的新进展[J]. 中国普外基础与临床杂志, 2010, 17(1):1-4.
- 4. Sayegh ME, Sano T, Dexter S, et al. TNM and Japanese staging systems for gastric cancer: how do they coexist?[J]. Gastric Cancer, 2004,7(3):140-148.
- 5. 徐岩, 徐惠绵.胃癌转移规律研究新进展[J].中国实用外科杂志, 2011, 31(08):666-669.
- 6. 日本胃癌学会編.胃癌取扱い規約(第14版)[M].東京:金原, 2010:5-15.
- 7. Sobin LH, Gospodarowicz MK, Wittekind C. International Union Against Cancer (UICC) TNM classification of malignant tumours[M]. 7th ed. New York:Wiley-Liss, 2010:117-126.
- 8. Noguchi M, Miyazaki I. Prognostic significance and surgical management of lymph node metastasis in gastric cancer[J]. Br J Surg, 1996,83(2):156-161.
- 9. Han KB, Jang YJ, Kim JH, et al. Clinical significance of the pattern of lymph node metastasis depending on the location of gastric cancer[J]. J Gastric Cancer, 2011,11(2):86-93.
- 10. 王振宁, 鲁翀, 徐惠绵. 胃上部癌淋巴结转移规律及其在外科治疗中的应用[J].中华实用外科杂志, 2002, 22(10):611-612.
- 11. Tanizawa Y, Terashima M. Lymph node dissection in the resection of gastric cancer:review of existing evidence[J]. Gastric Cancer, 2010,13(3):137-48.
- 12. 所剑. 胃癌的淋巴结清扫及意义[J]. 中国普外基础与临床杂志, 2010, 17(1):5-7.
- 13. Kunisaki C, Shimada H, Nomura M, et al. Distribution of lymph node metastasis in gastric carcinoma[J]. Hepatogastroenterology, 2006,53(69):468-472.
- 14. Kitamura K, Yamaguchi T, Nishida S, et al. The operative indications for proximal gastrectomy in patients with gastric cancer in the upper third of the stomach[J]. Surg Today, 1997,27(11):993-998.
- 15. Maruyama K, Gunvén P, Okabayashi K, et al. Lymph node metastases of gastric cancer. General pattern in 1 931 patients[J]. Ann Surg, 1989,210(5):596-602.
- 16. 黄宝俊, 鲁翀, 徐莹莹, 等. 292例早期胃癌淋巴结转移规律的研究[J].中华外科杂志, 2007, 45(3): 192-195.
- 17. 日本胃癌学会編.胃癌治療ガイドライン(第3版)[M].東京:金原, 2010:12.
- 18. 日本胃癌学会編.胃癌取扱い規約(第13版)[M].東京:金原, 2010:7-13.
- 19. Shen DF, Chen DW, Quan ZW, et al. Dissection of No.13 lymph node in radical gastrectomy for gastric carcinoma[J]. World J Gastroenterol,2008,14(6):936-938.
- 20. 朱海涛, 赵宜良, 吴云飞, 等.胃癌各组淋巴结的转移特点及其在实施合理根治术中的指导意义[J]. 中华肿瘤杂志, 2008,30(11):863-865.
- 21. Tokunaga M, Ohyama S, Hiki N, et al. Therapeutic value of lymph node dissection in advanced gastric cancer with macroscopic duodenum invasion: is the posterior pancreatic head lymph node dissection beneficial?[J]. Ann Surg Oncol, 2009,16(5):1241-1246.