目的 总结原发性腹膜后脂肪肉瘤（primary retroperitoneal liposarcoma，PRL）的临床病理特征、诊断及治疗方法。
方法 回顾性分析经手术和活检证实的23例PRL患者的临床病理资料。
结果 首发症状及体征表现为腹部肿块（91.3%，21/23），腹胀（56.5%，13/23）及腹痛（30.4%，7/23）。B超及CT的定位诊断准确率分别为66.7%（12/18）和85.7%（12/14）。首次手术肿瘤完整切除16例（69.6%），其中8例联合脏器切除； 部分切除3例（13.0%）； 仅行活检4例（17.4%）。PRL肿瘤完整切除术后复发率为75.0%（12/16）,该12例中再次手术8例（66.7%）可完全切除肿瘤。
结论 CT是诊断PRL的重要手段，优于B超； 手术以完整切除肿瘤为主，对侵犯脏器者采用累及脏器一并切除； 术后复发者可再次手术。
Citation：
杜嘉林,吴泽宇,万进. Diagnosis and Treatment of 23 Cases with Primary Retroperitoneal Liposarcoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2007, 14(6): 704-705. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
| 1. |
Dalton RR, Donohue JH, Mucha P, et al. Management of retroperitoneal sarcomas [J]. Surgery, 1989; 106(4)∶725.
|
| 2. |
唐光健， 王仪生， 姜涛， 等. 腹膜后原发肿瘤的CT诊断 [J]. 中华放射学杂志， 1996; 30(4)∶229.
|
| 3. |
Neville A, Herts BR. CT characteristics of primary retroperitoneal neoplasms [J]. Crit Rev Comput Tomogr, 2004; 45(4)∶247.
|
| 4. |
Erzen D, Sencar M, Novak J. Retroperitoneal sarcoma: 25 ye-ars of experience with aggressive surgical treatment at the institute of oncology, Ljubljana [J]. J Surg Oncol, 2005; 91(1)∶1.
|
| 5. |
Alldinger I, Yang Q, Pilarsky C, et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients [J]. Anticancer Res, 2006; 26(2B)∶1577.
|
| 6. |
郑树森， 徐骁. 原发性腹膜后及肠系膜脂肪肉瘤的诊断及外科治疗 [J]. 中国实用外科杂志， 2003； 23（9）∶540.
|
| 7. |
Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma [J]. Ann Surg， 2003; 238(3)∶358.
|
| 8. |
Neuhaus SJ, Barry P, Clark MA, et al. Surgical management of primary and recurrent retroperitoneal liposarcoma [J]. Br J Surg， 2005; 92(2)∶246.
|
| 9. |
Malerba M, Doglietto GB, Pacelli F, et al. Primary retroperitoneal soft tissue sarcomas: results of aggressive surgical treatment [J]. World J Surg， 1999; 23(7)∶670.
|
| 10. |
Serio G, Tenchini P, Nifosi F, et al. Surgical strategy in primary retroperitoneal tumours [J]. Br J Surg， 1989; 76(4)∶385.
|
- 1. Dalton RR, Donohue JH, Mucha P, et al. Management of retroperitoneal sarcomas [J]. Surgery, 1989; 106(4)∶725.
- 2. 唐光健， 王仪生， 姜涛， 等. 腹膜后原发肿瘤的CT诊断 [J]. 中华放射学杂志， 1996; 30(4)∶229.
- 3. Neville A, Herts BR. CT characteristics of primary retroperitoneal neoplasms [J]. Crit Rev Comput Tomogr, 2004; 45(4)∶247.
- 4. Erzen D, Sencar M, Novak J. Retroperitoneal sarcoma: 25 ye-ars of experience with aggressive surgical treatment at the institute of oncology, Ljubljana [J]. J Surg Oncol, 2005; 91(1)∶1.
- 5. Alldinger I, Yang Q, Pilarsky C, et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients [J]. Anticancer Res, 2006; 26(2B)∶1577.
- 6. 郑树森， 徐骁. 原发性腹膜后及肠系膜脂肪肉瘤的诊断及外科治疗 [J]. 中国实用外科杂志， 2003； 23（9）∶540.
- 7. Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma [J]. Ann Surg， 2003; 238(3)∶358.
- 8. Neuhaus SJ, Barry P, Clark MA, et al. Surgical management of primary and recurrent retroperitoneal liposarcoma [J]. Br J Surg， 2005; 92(2)∶246.
- 9. Malerba M, Doglietto GB, Pacelli F, et al. Primary retroperitoneal soft tissue sarcomas: results of aggressive surgical treatment [J]. World J Surg， 1999; 23(7)∶670.
- 10. Serio G, Tenchini P, Nifosi F, et al. Surgical strategy in primary retroperitoneal tumours [J]. Br J Surg， 1989; 76(4)∶385.
