Objective To explore the results of thrombolytic therapy of acute deep vein thrombosis of lower extremity. Methods The clinical data of 126 patients with acute deep vein thrombosis of lower extremity treated conservatively from Dec.1999 to Feb.2004 were analyzed retrospectively. Results All patients were divided into three groups: 26 of central, 33 of surrounding and 67 of combined by Doppler sonography. Combined medication was adopted in all cases, in which 85 cases (67.5%) were clinically cured, 34 cases (27.0%) had good results, and 5 cases (4.0%) recovered partially. Two cases (1.6%) didn’t get better. The total effective rate was 98.4% (124/126). Conclusion Most patients with acute deep vein thrombosis of lower extremity can get satisfied results with conservative treatment including thrombolysis and anticoagulation. Early diagnosis and appropriate medication are crucial.
Citation：
CHEN Hongqiang,LI Guangxin,XU Chongen,ZHANG Shuguang,YU Zhenhai,RUAN Changle.. Thrombolytic Therapy of Acute Deep Vein Thrombosis of Lower Extremity(Report of 126 Cases). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2006, 13(6): 665-667. doi:
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- 1. 吴在德主编. 外科学 [M]. 第5版. 北京： 人民卫生出版社， 2001∶690～691.
- 2. 李兆亭, 阮长乐主编. 实用普通外科 [M]. 第1版. 济南： 山东科学技术出版社， 2000∶376～377.
- 3. 吴少祯主编. 常见疾病的诊断与疗效判断标准 [M]. 第1版. 北京： 中国中医药出版社， 1999∶749～751.
- 4. Alexander P, Giangola G. Deep venous thrombosis and pulmonary embolism: diagnosis, prophylaxis, and treatment [J]. Ann Vasc Surg, 1999; 13(3)∶318.
- 5. 吴庆华. 急性下肢深静脉血栓的溶栓抗凝治疗 [J]. 中国实用外科杂志， 2003; 23（4）∶202.
- 6. 景在平， 赵 君. 深静脉血栓形成的诊断方法 [J]. 中国实用外科杂志， 2003; 23（4）∶196.
- 7. 张培华主编. 临床血管外科学 [M]. 第1版. 上海： 科学出版社， 2003∶501～502.
- 8. Schweizer J, Elix H, Altmann E, et al. Comparative results of thrombolysis treatment with rt-PA and urokinase: a pilot study [J]. Vasa, 1998; 27(3)∶167.
- 9. 郑明琪主编. 血栓栓塞的药物治疗 [M]. 第1版. 北京： 人民卫生出版社， 1989∶222～225.
- 10. Sherry S. Thrombolytic theraphy in acute myocardial infarction. A perspective [J]. Drugs, 1998; 33(Supply 3)∶1.
- 11. 国产重组链激酶协作组. 国产重组链激酶急性心梗溶栓治疗临床试验 [J]. 中华心血管杂志， 1997; 25（1）∶24.
- 12. 陈福真. 溶栓药物应用问题 [J]. 实用外科杂志, 1990; 9（1）∶451.
- 13. Graor RA， Risius B, Young JR. Low-dose strepokinase for selective thrombolysis: systematic effects and complications [J]. Radiology， 1984; 152(1)∶35.
