Using radioimmunoassay (RIA) and immunohistochemical LASB technique, the level of serum estradiol (E2), testosterone (T), progesterone (P), estrogen receptors (ER) and progesterone receptors (PR) in 30 male patients with gallstones were detected. The results showed that the level of serum P, E2/T and PR was higher. This suggests that the metabolic disorder of gonadal hormones play an important role in gallstone formation.
Citation:
Rui Jing,Wu Pei,Hou Yingyong,et al.. THE STUDY ON GONADAL HORMONES AND RECEPTORS IN MALE PATIENTS WITH GALLSTONES. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1999, 6(6): 361-362. doi:
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- 1. 顾悼云, 黄志强. 中国人胆结石特点(全国11 342份胆结石手术病例临床调查). 中华外科杂志, 1987; 25(6)∶321.
- 2. 赵浩亮, 李士骏, 张志利等. 女性胆囊结石患者血清垂体性腺激素的改变. 中华外科杂志, 1990; 28(1)∶33.
- 3. 陈学东. 胆囊功能变化与胆石病. 国外医学外科学分册, 1990; 17(3)∶133.
- 4. 芮景, 吴佩, 陈宜亭等. 胆结石患者垂体性腺轴激素变化的研究. 肝胆外科杂志, 1994; 2(1)∶26.
- 5. Scragg RK. Oral contraceptive pregnaney and endogenous oestroge in gallstone disease: a case controll study. Br Med J, 1984; 288(11)∶1795.
- 6. 王成友, 余宏铸, 张薇薇. 性激素类药物诱发胆囊结石的实验研究. 中国临床药理学与治疗学杂志, 1996; 1(1)∶29.
- 7. 薛涣洲, 李士骏, 赵秉化等. 雌性激素与胆结石成因的实验研究. 中华外科杂志, 1989; 27(11)∶686.
- 8. Hoover EL, Jaffe BM, Webb H, et al. Effects of females sex hormons and pragnancy on gallbladder profaglandin synthesis. Arch Surg, 1988; 123(6)∶765.
- 9. Rege RV, Moore EW. Evidence for H+ sceretion by the in vivo canine gallbladder. Gastroenterology, 1987; 92(2)∶281.