Pre-and postoperative perfusion of thermochemotherapy was used in 25 cases of advanced malignant tumors of digestive tract.There were on significant changes in hepatic and renal functions after perfusions.The erythrocyte,leukocyte and platelet counts reduced in the second and third week after the beginning
of perfusion,but rose up in the 4th week.A 2-year follow-up revealed that 23 patients were still alive without recurrence or metastases except 2cases died in the 6th and the 9th month after treatment.We claim that intraperitoneal thermochemotherapy is a simple and safe method. A prospective study is still necessary
in deciding the dose and course.
Citation：
Chen Jiayong,Zhang Jie,Tan Jing,et al.. INTRAPERITONEAL PERFUSIVE THERMOCHEMOTHERAPY FOR PREVENTION OF POSTOPERATIVE RECURRANCE OF ADVANCED MALIGNANT TUMORS IN GASTROINTESTINAL TRACT. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1997, 4(1): 17-19. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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- 1. Hamaxoe R,Maeta M,Kaibara N.Intraperitoneal thermochemotherapy for prevention of peritoneal recurrence of gastric cancer.Cancer,1994;73(8):2048.
- 2. Case AW,Million RR,Pfaff WW.Patterns of recurrence following surgery alone for adenocarcinoma of the colon and rectum.Cancer,1976;37:2861.
- 3. Russell AH,Tong D,Dawson LE,et al.Adenocarcinoma of the proximal colon.Sites of initial dissemination and patterns of recurrence following surgery alone.Cancer,1984;53:360.
- 4. Cunliffe WJ,Sugarbaker PH.Gastrointestinal malignancy:rationale for adjuvant therapy using early postoperative intraperitoneal chemotherapy.Br J Surg,1989;76:1082.
- 5. Archer S,Gray B. Intraperitoneal 5-fluorouracil infusion for treatment of both peritoneal and liver micrometastases.Surgery,1990; 108(3):502.
- 6. Markman M.Melphalan and cytarabiner administered intraperitoneally as single agents and combination intraperitoneal chemothrapy with cisplatin and cytarabine.Semin Oncol,1985; 12:33.
- 7. Sugarbaker PH,Graves T,DeBruijn EA,et al. Early postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer:pharmacological studies.Cancer Res,1990;108(3):5790.
- 8. Sugarbaker PH,Gianola FJ,Speyer JC,et al. Prospective,randomized trial of intravenous versus intraperitoneal 5-fluorouracil in patients with advanced primary colon or rectal cancer.Surgery,1985; 93(3):414.
- 9. Martine MJ,Abrams J,Dodion PF,et al.Intraperitoneal chemotherapy with cisplatin and melphalan.Cancer Insti,1988;80(40):1118.
- 10. Mcive JG,Dikhodd T,Van der Heide,et al. Infections peritonitis in patients receiving intraperitoneal chemotherapy.Proc Am Assor Cancer Res,1985;26:162.
