目的 探讨先天性心脏病合并肺动脉瓣感染性心内膜炎的外科治疗方法和效果。 方法 2009年1月至2012年1月第二军医大学长海医院收治先天性心脏病合并肺动脉瓣感染性心内膜炎患者6例,男1例,女5例;年龄8~41 (24.8±11.8)岁。动脉导管未闭(PDA)4例,PDA合并先天性主动脉瓣狭窄1例,室间隔缺损(VSD)合并三尖瓣反流1例。3例行PDA结扎+肺动脉内赘生物清除术,1例行PDA结扎+肺动脉瓣赘生物切除术,1例行PDA结扎+肺动脉瓣赘生物切除术+主动脉瓣置换术(AVR,置换19 mm CarboMetics环上机械主动脉瓣),1例肺动脉瓣膜破坏严重,行VSD修补+右心室流出道赘生物清除+右心室流出道拓宽+三尖瓣成形术+肺动脉生物瓣置换术(置换27 mm HancockⅡ型生物瓣)。 结果 6例患者术后均恢复良好,无围术期死亡和心内膜炎复发。所有患者复查超声心动图提示,未见赘生物、残余漏、瓣周漏等并发症。术后随访6个月~3年中,患者临床症状完全消失,均无明显不适。术后心功能恢复至Ⅰ级5例,Ⅱ级1例。 结论 对于先天性心脏病合并肺动脉瓣感染性心内膜炎患者,正确把握手术时机,积极行外科手术治疗是最有效的治疗方法。
Citation:
余咏潮,徐志云,徐激斌,唐昊,唐杨锋. 先天性心脏病合并肺动脉瓣感染性心内膜炎的外科治疗. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2013, 20(1): 103-102. doi:
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Ramadan FB, Beanlands DS, Burwash IG. Isolated pulmonic valve endocarditis in healthy hearts:a case report and review of the literature. Can J Cardiol, 2000, 16 (10):1282-1288.
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Vu M, Harrison BA, Destephano C, et al. Endocarditis, vegetation, and perforation of the pulmonary valve. J Cardiothorac Vasc Anesth, 2008, 22 (2):261-262.
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周建平, 周伟, 李伟阳. 静脉药瘾所致感染性心内膜炎的外科治疗. 实用医学杂志, 2008, 24 (5):796-797.
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Durack DT, Andrea SL, Bright DK, et al. New criteria for diagnosis of infective endocarditis:utilization of specific echocardiographic findings. Am J Med, 1994, 96 (3):200-209.
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Di Filippo S, Delahaye F, Semiond B, et al. Current patterns of infective endocarditis in congenital heart disease. Eur Heart J, 2006, 92 (10):1490-1495.
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Habib G, Badano L, Tribouilloy C, et al. Recommendations for the practice of echocardiography in infective endocarditis. Eur J Echocardiogr, 2010, 11 (2):202-219.
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李潭, 杨军, 马春燕, 等. 超声评价先天性心脏病合并感染性心内膜炎的价值. 中华临床医师杂志:电子版, 2012, 06 (5):1360-1361.
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Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009):The task force on the prevention, diagnosis, and treatment of Infective endoearditis of the European Society of Cardiology (ESC). Eur Heart J, 2009, 30 (19):2369-2413.
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Rohn V, Slais M, Kotulák T, et al. Pulmonary valve replacement for pacing electrodes related bacterial endocarditis. Ann Thorac Surg, 2008, 85 (6):2128-2130.
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刘宝玉, 姜建青, 周凯, 等. 感染性心内膜炎的外科治疗. 中国胸心血管外科临床杂志, 2007, 14 (6):471-472.
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Musci M, Siniawski H, Pasic M, et al. Surgical treatment of right-sided active infective endocarditis with or without involvement of the left heart:20-year single center experience. Eur J Cardiothorac Surg, 2007, 32 (1):118-125.
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- 1. Ramadan FB, Beanlands DS, Burwash IG. Isolated pulmonic valve endocarditis in healthy hearts:a case report and review of the literature. Can J Cardiol, 2000, 16 (10):1282-1288.
- 2. Vu M, Harrison BA, Destephano C, et al. Endocarditis, vegetation, and perforation of the pulmonary valve. J Cardiothorac Vasc Anesth, 2008, 22 (2):261-262.
- 3. 周建平, 周伟, 李伟阳. 静脉药瘾所致感染性心内膜炎的外科治疗. 实用医学杂志, 2008, 24 (5):796-797.
- 4. Durack DT, Andrea SL, Bright DK, et al. New criteria for diagnosis of infective endocarditis:utilization of specific echocardiographic findings. Am J Med, 1994, 96 (3):200-209.
- 5. Di Filippo S, Delahaye F, Semiond B, et al. Current patterns of infective endocarditis in congenital heart disease. Eur Heart J, 2006, 92 (10):1490-1495.
- 6. Habib G, Badano L, Tribouilloy C, et al. Recommendations for the practice of echocardiography in infective endocarditis. Eur J Echocardiogr, 2010, 11 (2):202-219.
- 7. 李潭, 杨军, 马春燕, 等. 超声评价先天性心脏病合并感染性心内膜炎的价值. 中华临床医师杂志:电子版, 2012, 06 (5):1360-1361.
- 8. Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009):The task force on the prevention, diagnosis, and treatment of Infective endoearditis of the European Society of Cardiology (ESC). Eur Heart J, 2009, 30 (19):2369-2413.
- 9. Rohn V, Slais M, Kotulák T, et al. Pulmonary valve replacement for pacing electrodes related bacterial endocarditis. Ann Thorac Surg, 2008, 85 (6):2128-2130.
- 10. 刘宝玉, 姜建青, 周凯, 等. 感染性心内膜炎的外科治疗. 中国胸心血管外科临床杂志, 2007, 14 (6):471-472.
- 11. Musci M, Siniawski H, Pasic M, et al. Surgical treatment of right-sided active infective endocarditis with or without involvement of the left heart:20-year single center experience. Eur J Cardiothorac Surg, 2007, 32 (1):118-125.