目的 探讨三尖瓣关闭不全(TI)外科治疗时机、手术方式与疗效的关系。 方法 回顾性分析中山大学附属第一医院2003年1月至2010年10月手术治疗的282例TI患者的临床资料,其中男115例,女167例;年龄(42.00±15.90) 岁。按手术方式分为三尖瓣置换术(TVR)34例,三尖瓣成形术(TVP)248例(包括改良De Vega成形术、Kay’s成形术、瓣裂修补术、人工瓣环成形术),评价患者疗效。 结果 术后早期死亡13例,死于低心排血量综合征7例,室性心律失常3例,感染性休克2例,心脏破裂1例。早期死亡率为4.61% (13/282)。手术时间(167.47±37.34) min,体外循环时间(109.67±27.98) min,主动脉阻断时间(66.20±18.42) min,住院时间(16.46±5.29) d。术后1年随访249例,三尖瓣反流改善总有效率为90.76% (226/249)),其中改良De Vega成形术有效率为91.41% (117/128),Kay’s成形术为80.49% (33/41),瓣裂修补术为92.31% (24/26),人工瓣环成形术为96.00% (24/25),TVP为96.55%(28/29)。术后肺动脉压较术前明显降低(P<0.01),右心室内径缩小。 结论 对中-重度TI或瓣环明显扩大者,应积极手术干预;Kay’s成形术后三尖瓣反流复发率较高,人工瓣环成形术效果良好;对于瓣膜发育不良或毁损者应首选TVR。
Citation:
王晓进,张希,杨小月,陈冠雄,刘云奇. 三尖瓣关闭不全外科治疗282例. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2012, 19(5): 576-578. doi:
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- 1. Matsunaga A, Duran CM. Progression of tricuspid regurgitation after repaired functional ischemic mitral regurgitation. Circulation, 2005, 112 (9 Suppl):I453-I457.
- 2. Mccarthy PM, Bhudia SK, Rajeswaran J, et al. Tricuspid valve repair:durability and risk factors for failure. J Thorac Cardiovasc Surg, 2004, 127 (3):674-685.
- 3. Colombo T, Russo C, Ciliberto GR, et al. Tricuspid regurgitation secondary to mitral valve disease:tricuspid annulus function as guide to tricuspid valve repair. Cardiovasc Surg, 2001, 9 (4):369-377.
- 4. Vahanian A, Baumgartner H, Bax J, et al. Guidelines on the management of valvular heart disease:The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology. Eur Heart J, 2007, 28 (2):230-268.
- 5. Dreyfus DG. Secondary tricuspid regurgitation or dilatation:which should be the criteria for surgical repair ? Ann Thorac Surg, 2005, 79 (1):127-132.
- 6. Antunes MJ, Barlow JB. Management of tricuspid valve regurgitation. Heart, 2007, 93 (2):271-276.
- 7. Bernal MJ. Reoperations after tricuspid valve repair. J Thorac Cardiovasc Surg, 2005, 130 (2):498-503.
- 8. Morishita A. Long-term results after De Vega’s tricuspid annuloplasty. J Cardiovasc Surg (Torino), 2002, 43 (6):773-777.
- 9. 谢周良, 葛振伟, 杨志远, 等. 功能性三尖瓣关闭不全成形效果观察. 医药论坛杂志, 2010, 31 (18):32-33, 36..
- 10. Shah PM. Tricuspid and pulmonary valve disease evaluation and management. Rev Esp Cardiol, 2010, 63 (11):1349-1365.
- 11. Kunadian B. Should the tricuspid valve be replaced with a mechanical or biological valve ? Interact Cardiovasc Thorac Surg, 2007, 6 (4):551-557.