The Method of Tissue Engineering in Spinal Cord Injury Scaffold Forming Technology’s Exploration_West China Medical Journal

Authors：

1Chengdu Medical College of 2006 Clinical Undergraduate Courses; 2Chengdu Medical College of 2005 Level of Pharmacy Undergraduate Courses; 3Chengdu Medical College of Experimental Technology Center, Chengdu 610083, China;

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Keywords：

脊髓损伤; 成形技术; 组织工程

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组织工程的提出、建立和发展,为最终实现脊髓损伤的修复和真正意义上的结构、形态与功能重建开辟了新的途径。支架的生物活性、三维结构和表面微观结构,材料的降解性等众多因素都对细胞增殖,分化和组织形成有明显影响。组织工程的发展也将改变传统的医学模式,使得再生医学得以进一步发展,并最终用于疾病的治疗。

Citation： CHEN Guo,OU Lin,ZHAO Renjie,et al.. The Method of Tissue Engineering in Spinal Cord Injury Scaffold Forming Technology’s Exploration. West China Medical Journal, 2009, 24(5): 1308-1309. doi: Copy

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1. ALBERT T, RAVAUD J F, the Tetrafigap group. Rehabilitation of spinal cord injury in France: a nationwide multicentre study of incidence and regional disparities[J]. Spinal Cord,2005,43:357365.
2. 朱巍,贾连顺,邵将,等.急性颈髓损伤死亡预判因素分析[J].中国创伤杂志,2008,24(3):205-207.
3. 万虹,李德志,杨飞,等.许旺细胞与PLGA共同移植于大鼠全横断脊髓损伤的实验研究[J].中华外科杂志,2007,45(12):843-846.
4. 陈少强,林建华.脊髓间充质干细胞移植治疗脊髓损伤的研究现状[J].中国修复重建外科杂志,2007,21(5):507-511.
5. 雷德强,赵洪洋,刘如思.脊髓损伤的治疗进展[J].中国现代神经疾病杂志,2008,8(1):71-74.
6. 钱苏林,陈安民.脊髓损伤药物治疗新进展[J].中国骨伤,2008,21(2):164-166.
7. 陈际达,崔磊,刘伟,等.溶剂浇铸／颗粒沥滤技术制备组织工程支架材料[J].中国生物工程杂志,2003,23(4):32-36.
8. 唐圣奎,谢军军,熊杰.基于不同溶剂静电纺再生丝素蛋白组织工程支架的研究与进展[J].中国组织工程研究与临床康复,2008,12(45):8889-8892.
9. WIDMER M S, GUPTA P K, LU L, et al. Manufacture of porous biodegradable polymer conduits by an extrusion process for guided tissue regeneration[J]. Biomaterials,1998,19:19451955.
10. JUNG H D, YOOK S W, KIM H E, et al. Fabrication of titanium scaffolds with porosity and pore size gradients by sequential freeze casting[J]. Mater Lett,2009,63(17):1545-1547.
11. SREERAM K J, NIDHIN M, NAIR B U. Synthesis of aligned hematite nanoparticles on chitosanalginate films[J]. Colloids Surfaces B: Biointerfaces,2009,71(2):260-267.
12. ACOSTA M A, YMELELEKIA P, KOSTOV Y V, et al. Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds[J]. Biomaterials,2009,30(17):3068-3074.
13. SALERNO A, GUARNIERI D, IANNONE M, et al. Engineered μbimodal poly(εcaprolactone) porous scaffold for enhanced hMSC colonization and proliferation[J]. Acta Biomaterialia,2009,5(4):1082-1093.
14. BOISSARD C I R, BOURBAN P E, TAMI A E, et al. Eglinanohydroxyapatite/poly(esterurethane) scaffold for bone tissue engineering[J]. In Press, Accepted Manuscript, Available online 13 May 2009.
15. DELAMARCHE E, BERNARD A, SCHMID H, et al. Microfluidic Networks for surfaces using microfluidic networks[J]. Science,1998,276:779-781.
16. 沙菁契,侯丽雅,章维一.基于微立体光刻技术的组织支架的制备[J].华中科技大学学报,2007,35:61-63.
17. 谭俊铭,史建刚,贾连顺,等.脊髓损伤后促进轴突再生的治疗进展[J].中国治疗骨伤杂志,2008,10(2):189-191.

West China Medical Journal

The Method of Tissue Engineering in Spinal Cord Injury Scaffold Forming Technology’s Exploration

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