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板层巩膜切除手术治疗葡萄膜渗漏综合征的疗效观察

早产儿视网膜病变筛查相关意外和并发症分析

视网膜脱离术后植人物前移三例

视网膜脱离术后植入物前移是一种较少见的并发症．报告3例植入物侵蚀肌肉，穿过直肌止端前移，术中均未切断肌肉，其中2例出现眼球运动障碍，对此并发症的发生机理进行了简要讨论． （中华眼底病杂志，1994，10：38-39）

应用液压冲击颅脑损伤仪建立大鼠外伤性视神经损伤动物模型

Objective　To observe whether the animal model of optic nerve injury in rats can be set up by fluid percussion brain injury device (FPI) or not.Methods　Seventyone healthy female Wister rats were randomly divided into 2 groups, inlcuding model group with 66 rats and control group with 5 rats.The rats in model group were randomly divided into 3 groups. Eight rats in group 1 were examined by flashvisual evoked potential (F-VEP) and magnetic resonance imaging (MRI) examines before and 1, 3 days,1,2,4,6,and 8 weeks after injury; 56 rats in group 2 were randomly divided into 7 subgroups with 8 rats in each subgroup，and were detected by histopathological and terminal deoxynucleotidyl transferasemediated dUTP nick end labeling (TUNEL) apoptosis examines 1, 3 days, 1,2,4,6,8 weeks after injury；2 rats in group 3 were examined by electron microscopy 4 and 8 weeks after injury.According to the degree of injury, the injured eyes were divided into 2 groups including severe injury group with the beat pressure of （699.14plusmn;60.79） kPa and mild injury group with the beat pressure of （243.18plusmn;20.26） kPa.The right and left eyes in rats in each group were in severe and mild injury group, respectively.Results　One day after injury, the latency duration of FVEP prolonged in severe injury group，wich differed much form which in the normal control group (P＜0.05)；the amplitude was gradually reduced during the first 2 weeks after injury and kept steady after that (P＞0.05). The latency duration prolonged in mild injury group,and its difference with the normal control group was statistically significant (P＜0.05)；the amplitude was gradually reduced during the first 4 weeks after injury and kept steady after that (P＞0.05). The abnormal high signal could be seen on optic nerve 1 day after injury, and was still obvious 8 weeks later. The results of histopathological examination showed ruptured capillary in ganglion cell layer 1 day after injury;retinal ganglion cells without nucleus could be seen 4 weeks after injury. The apoptosis of positive cells was found in each layer of the retina 3 days after injury.TUNEL results indicated that the number of apoptotic positive cells increased significantly 1-2 weeks after injury.Conclusion　An animal model of optic nerve injury can be successfully set up using FPI in rats.

登革热患者黄斑病变一例

先天性视网膜动静脉畸形并发视网膜分支静脉阻塞二例

视盘血管瘤一例

Clinical Application and the Prevention of Complications of Perclose ProGlide Suture-mediated Closure System after Percutaneous Coronary Intervention

【摘要】　目的　评价经皮冠状动脉成形术（percutaneous coronary interventions，PCI）术后，穿刺股动脉应用Perclose ProGlide血管缝合器止血的安全性、可靠性及对常见并发症的防范。　方法　2007年4月-2009年5月，收治217例经股动脉PCI术后患者，根据术后是否使用血管缝合器将患者随机分成血管缝合器组（105例）和对照组（经手法压迫止血112例）。观察记录两组患者下肢制动时间及血管并发症等。　结果　血管缝合器组103例操作成功（98.1%），2例失败；对照组成功112例（100%）。两组成功率比较，差异无统计学意义（Pgt;0.05）。血管缝合器组和对照组患者下肢制动时间分别为（4.1±1.2）和（25.0±3.1）h，两组比较，差异有统计学意义（Plt;0.01）。术后两组并发症发生率比较，差异无统计学意义（Pgt;0.05）。　结论　血管缝合器是一种安全、可靠的止血方法，可明显缩短制动时间，无明显的穿刺部位血管并发症，熟练操作可减少并发症的发生。【Abstract】　Objective　To evaluate the safety of Perclose ProGlide Suture-Mediated Closure System applied to femoral artery puncture site after percutaneous coronary interventions (PCI) and to explore the prevention of possible common complications.　Methods　A total of 217 patients who underwent PCI from April 2007 to May 2009 were randomly divided into Perclose ProGlide group (105 patients, hemostasis by Perclose ProGlide Suture-Mediated Closure System) and control group (112 patients, hemostasis by compression). The Lower-limb braking time and the complications were recorded and analyzed.　Results　The successful rate was 98.1% (103 patients) in Perclose ProGlide group, and 100% (112 patients) in the control group; the difference between the two groups was not significant (Pgt;0.05). But there was a significant difference (Plt;0.01) in Lower-limb braking time between the two groups[(4.1±1.2) and (25±3.1) hours]. The post-operative complications between the two groups didn’t differ much.　Conclusions　Perclose ProGlide Suture-Mediated Closure System is a safe,effective and simple method after percutaneous coronary intervention to achieve immediate hemastasis. Skillfully processing may reduce the vascular complications.

侧颅底肿瘤术后并发症的观察及护理

【摘要】　目的　总结侧颅底肿瘤术后并发症的观察及护理经验。　方法　对2005年4月-2011年1月接受侧颅底肿瘤手术的36例患者的护理方法及特点进行回顾性分析。　结果　36例患者中发生并发症5例，发生率为13.8%，其中脑脊液漏2例，面瘫2例，局部感染1例，经精心治疗和护理后全部好转出院。　结论　术前正确评估病症，术中谨慎操作，术后严密观察病情及精心护理，是患者获得康复重要因素。

高度近视黄斑裂孔患眼脉络膜厚度观察