west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "心内直视手术" 19 results
  • 心内直视手术中鱼精蛋白毒性反应的发生及处理

    目的 分析心内直视手术中鱼精蛋白毒性反应发生情况、临床特点,探讨处理措施。 方法 2001年1月~2006年1月,连续行1 163例心内直视手术中发生鱼精蛋白毒性反应31例,其中轻度反应(血压下降lt;30mmHg)26例,中度、重度反应(中度反应血压下降30~49mmHg,重度反应血压下降≥50mmHg)5例;低血压型28例,过敏反应/类过敏反应型2例,肺血管收缩型1例。所有患者均给予立即停止使用鱼精蛋白或减慢鱼精蛋白泵入速度、补充血容量、抗过敏、血管活性药物或再次体外循环治疗。 结果 26例出现轻度鱼精蛋白毒性反应者经停止使用或减慢鱼精蛋白泵入速度及相应治疗后,均很快好转;5例出现中度、重度鱼精蛋白毒性反应者,经停止使用鱼精蛋白、抗过敏、补充血容量、血管活性药物和再次体外循环支持, 4例好转,1例死亡。27例门诊随访3个月,恢复正常学习和工作。 结论 心内直视手术中鱼精蛋白毒性反应发生率高,中度、重度反应者死亡率高。鱼精蛋白毒性反应的发生与其用量和使用方法密切有关,充分认识鱼精蛋白毒性反应的临床特点,精确鱼精蛋白用量和改进使用方法能在一定程度上防治毒性反应的发生。

    Release date:2016-08-30 06:15 Export PDF Favorites Scan
  • 7262例体外循环管理经验总结

    目的总结体外循环(CPB)管理的经验及教训,为更安全的CPB方式提供参考。方法回顾性分析我院1964年2月~2004年12月施行的CPB心内直视手术7262例患者的临床资料,并对硬件设备、转流技术、灌注师经验、术中监测及心肌保护等方面进行分析,其中3748例患者采用心脏不停跳CPB。结果全组死亡248例,总死亡率3.4%(248/7262)。1964年2月~1983年12月施行CPB手术464例,死亡52例,死亡率11.2%;1984年1月~1996年12月施行CPB手术1709例,死亡78例,死亡率4.6%;1997年1月~2004年12月施行CPB手术5089例,死亡118例,死亡率2.3%;1997年3月~2004年12月,对3748例患者采用心脏不停跳CPB,手术顺利,未发生与CPg相关的并发症及死亡。结论灌注师的经验和硬件设备的完善、使用高质量的人工心肺机和氧合器、多种转流技术的应用、完善的监测系统等可明显提高CPB的安全性。心脏不停跳下CPB是安全且易于管理的一种方式。

    Release date:2016-08-30 06:18 Export PDF Favorites Scan
  • 风湿性心脏病与冠心病患者围术期心肌酶变化的比较

    目的 对风湿性心脏病(RHD组)和冠状动脉粥样硬化性心脏病(CAHD组)患者围术期心肌酶的变化进行动态观察与比较,探讨病种是否会影响心肌酶的释放与恢复. 方法 手术前1天、术后1天、3天、5天和8天晨分别取静脉血,测定两组患者血清天门冬酸氨基转移酶(AST)、肌酸激酶(CK)及其同工酶MB(CK-MB)、乳酸脱氢酶(LDH)、乳酸脱氢酶同工酶1( LDH-1). 结果 两组患者术前5种心肌酶均在正常范围,术后1天分别升高到术前的2~13倍(P<0.05),术后3天均有不同程度的恢复,到术后8天除了两组的LDH和LDH-1仍明显高于术前外,其它酶的释放量均已恢复到正常水平;术后心肌酶的释放量以RHD组的患者为高(P<0.05). 结论 择期手术的RHD和CAHD患者术前心肌酶的释放量在正常水平.术后心肌酶释放的高峰时间及心肌酶的恢复次序是一致的,术后RHD组患者心肌酶的释放量较CAHD组患者高.判断术后心肌损伤的恢复应以LDH和LDH-1的恢复为标准.

    Release date:2016-08-30 06:31 Export PDF Favorites Scan
  • Efficacy of Radiofrequency Modified Maze Procedure Combined with Open-heart Surgery for Atrial Fibrillation

    Objective To evaluate the efficacy of Radiofrequency (RF) modified maze procedure combined with open-heart surgery for atrial fibrillation (AF). Methods From January 2003 to October 2004, 66 patients underwent the RF modified maze Ⅲ procedure for AF combined with open-heart surgery. The preoperative and postoperative indexes of electrocardiogram and echoeardiogram were compared through retrospective analysis and follow-up. Postoperative cardiac function and thromboembolie events were evaluated through telephone and mail. Results The time needed for RF modified maze Ⅲ was 18.61±3.56 min. There were no hospital deaths and the complications was 15.15%(10/66). Follow-up duration was 14.25±6.47 months with 95.45%(63/66) completion. At the lastest follow-up, the rate of freedom from AF was 80.95% (51/63)and the rate of restoration to sinus rhythm was 74.60%(47/63). No thromboembolic events was seen. 77.78%(49/63) of patients were in NYHA class Ⅰ. Significant decrease was seen in both left atrial dimension (LAD) and left ventricular dimension (LVD)(P〈0.01) more than 6 months after operation. Conclusion RF modified maze Ⅲ procedure as an adjunctive procedure is safe, time-sparing and effective in eliminating AF.

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • 鼓泡式改良左心引流管在心内直视手术中的应用

    目的介绍鼓泡式改良左心引流管在心内直视手术中的应用。方法138例先天性心脏病、风湿性心瓣膜病及其它心脏疾病患者在心内直视手术中采用鼓泡式改良左心引流管进行左心减压引流。结果全部患者置入鼓泡式改良左心引流管顺利,拔除不困难,引流效果良好。结论鼓泡式改良左心引流管在负压吸引过程中侧孔不容易因吸附被软组织堵塞,引流效果可靠。

    Release date:2016-08-30 06:25 Export PDF Favorites Scan
  • 先天性心脏病心脏不停跳心内直视手术

    摘要 目的 介绍体外循环心脏不停跳下心内直视手术治疗先天性心脏病心内畸形的应用体会。 方法 327例先天性心脏病心内畸形行浅低温体外循环心脏不停跳心内直视手术。常规建立体外循环,置左心房引流管,降温至32±1℃并维持,仅阻断上、下腔静脉,不阻断升主动脉,维持灌注压在60mmHg左右,在心脏不停跳下施行心脏畸形矫正术,方法同心脏停搏手术。 结果 死亡7例,死亡率2.1%,其余均痊愈出院,随访1~13个月,恢复良好。 结论 心脏不停跳下心内直视手术有较好的心肌保护作用,能减少并发症的发生,并简化操作,缩短体外循环时间。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • A Clinical Analysis of 215 Cases of Open Heart Operation with Mild Hypothermia in Beating Heart

    目的:总结215例浅低温体外循环下不停跳心内直视手术的临床应用经验。方法:215例行心脏不停跳心内直视手术病例,并行循环者阻断上下腔静脉而不阻断升主动脉,不使用心脏停跳液;逆行灌注者,阻断升主动脉后经冠状静脉窦逆行持续灌注机器氧合血,鼻咽温度在(33±1)℃,均在心脏空跳下完成心内直视手术。结果:心脏手术完毕后顺利停机,术后血液动力学平稳,低心输出量综合征发生率低,无1例发生神经系统并发症及空气栓塞,早期死亡率0.93%(2/215)。结论:浅低温体外循环下不停跳心内直视手术技术安全可行,是一种接近生理状态的心肌保护方法,可应用于绝大部份心内直视手术。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • 逆行灌注心脏不停跳双瓣膜置换术围术期心肌细胞凋亡及Bcl-2,Bax的表达

    目的观察逆行灌注心脏不停跳双瓣膜置换术围术期心肌细胞凋亡及Bcl-2,Bax蛋白表达的变化。方法将26例风湿性心脏病患者分为两组,实验组:14例,阻断主动脉后浅低温逆行灌注持续给予氧合血,使心脏缓慢跳动(40~50次/分);对照组:12例,中度低温阻断主动脉后根部灌注高钾含血停搏液,待心脏停搏后改为逆行灌注。术中多时点检测血浆肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白T(cTnT)的含量;分别于体外循环(CPB)前,CPB后30min留取右心房标本,检测心肌凋亡细胞及免疫组化法测定心肌细胞Bcl-2和Bax蛋白表达。结果与CPB前比较,主动脉阻断30min时两组CK-MB、cTnT和心肌细胞凋亡数明显升高(P〈0.01),Bax表达明显降低(P〈0.01),实验组Bcl-2表达降低不明显(P〉0.05),而对照组Bcl-2表达降低明显(P〈0.01)。与对照组比较,主动脉阻断30min后实验组CK-MB、cTnT和心肌细胞凋亡数明显降低(P〈0.05),Bcl-2表达明显升高(P〈0.01)。结论逆行灌注心脏不停跳双瓣膜置换术与心脏停搏手术相比较,对心肌细胞凋亡的影响较小,可能与维持Bcl-2蛋白表达水平,抑制Bcl-2/Bax基因向Bax偏移等因素有关。

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • 右腋下小切口体外循环心内直视手术270例

    目的 总结右腋下小切口在常见先天性心脏病手术中的应用经验。 方法 回顾性分析济宁医学院附属医院2009年10月至2011年6月采用右腋下小切口经第4肋间进胸,在体外循环下施行心内畸形矫治手术270例患者的临床资料,其中男132例,女138例;年龄3个月~9岁 (3.0±1.6) 岁,行室间隔缺损(VSD)修补术132例,房间隔缺损(ASD)修补术50例,ASD修补术+部分型肺静脉异位引流(PAPVC)矫治术12例,部分型房室管畸形(PECD)矫治术15例,VSD+ASD修补术26例,法洛四联症根治术35例。 结果 全组无手术死亡,无二次开胸止血,平均住院时间9 d,平均住ICU 1.6 d。发生右肺不张3例,右侧气胸2例,阵发性室上性心动过速1例,Ⅱ°房室传导阻滞1例。术后全部患者均获得随访,随访时间1~16个月,随访期间3例VSD术后发生小于2 mm的残余漏,其余患者恢复良好。 结论 对具有该术式适应证的患者经右腋下小切口行心内直视手术,有安全可靠、创伤小、美观等优点。

    Release date:2016-08-30 05:50 Export PDF Favorites Scan
  • Clinical Analysis of Cardiac Surgery Concomitant with Bipolar Radiofrequency Ablation for Atrial Fibrillation

    ObjectiveTo evaluate the efficacy and safety of cardiac surgery concomitant with bipolar radiofrequency ablation(BRFA) for the patients with heart disease and atrial fibrillation(AF). MethodsFrom April 2008 to September 2014, clinical data of 167 patients(43 males, 124 females) of organic-heart-disease patients combined with atrial fibrillation were analyzed retrospectively in our hospital. Within 167 patients, 102 patients underwent bipolar radiofrequency ablation without aortic cross-clamping were as a trial group and the other 65 patients underwent cardiac surgery and bipolar radiofrequency ablation with aortic cross-clamping were as a control group. And there were no significant difference in the age and gender between the two groups. ResultsThe time of radiofrequency ablation was 23.1±5.0 minutes in all the patients and there was no significant difference between the two groups(P=0.279). The extracorporeal circulation time was 156.6±56.4 minutes and the aortic cross-clamping time was 82.1±42.6 minutes. There was a significant difference between two groups in extracorporeal circulation time and aortic cross-clamping time. One patient underwent bipolar radiofrequency ablation with aortic cross-clamping died of severe pulmonary infection and multiple organ dysfunction syndrome(MODS) in one month after the surgery. The duration of follow-up was 1-77(35.3±3.5) months. The sinus rhyme conversion rate was estimated by electrocardiogram(ECG) in 1 month, 3 months, 6 months, 12 months, 36 months, 60 months after operation. The sinus rhyme conversion rates were 85.3%(133/156), 83.4%(126/151), 82.7%(115/139), 77.0%(94/122), 75.9%(41/54), and 72.0%(18/25). There was no significant difference during the follow-up in all of the sinus rhyme conversion rate. During the fellow-up, 2 patients died. One died after 1 month and another died after 6 months after their hospital-discharges. ConclusionThe efficacy and safety of cardiac surgery concomitant with bipolar radiofrequency ablation is satisfied. It can reduce the time of myocardial ischemia in bipolar radiofrequency ablation without aortic cross-clamping. It is beneficial to critical patients.

    Release date: Export PDF Favorites Scan
2 pages Previous 1 2 Next

Format

Content