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find Keyword "文献复习" 15 results
  • Reported One Case of the Renal Transplant between Identical Twins and Reviewed Literatures

    摘要:目的: 报道同卵双生子间肾移植效果,探讨免疫抑制剂及激素的使用、鉴定同卵双生子的方法以及术后随访。 方法 :个案报道结合文献综述。 结果 :手术获得成功。术后随访8月,患者恢复良好。 结论 :同卵双生间的肾移植安全有效,术后不需要使用免疫抑制剂也能维持移植肾功能正常。Abstract: Objective: Reported the effects of renal transplantation between identical twins,explored the use of immunosuppressive drugs and glucocorticoid, identification method of the identical twins and postoperative followup . Methods :Combining case report and literature review. Results :The operation is success.Followup in 8 months,the patient recover well. Conclusion : The renal transplantation between identical twins is safe and effective,the immunosuppressant is not need for the postoperative patients to maintain the graft`s function.

    Release date:2016-09-08 10:12 Export PDF Favorites Scan
  • Common Variable Immune Deficiency Combined with Celiac Disease: A Case Report and Literatures Review

    ObjectiveTo enhance the understanding of common variable immune deficiency (CVID) combined with celiac disease in order to diagnose and treat the disease as early as possible and delay its complications through the treatment of the disease and study on related literatures. MethodThe experience of diagnosing and treating one case of CVID combined with celiac disease in November 2013 was reported in the present study, and the related literatures were reviewed. ResultsAfter strict gluten-free diet and infusion of intravenous immune globulin, the patient's diarrhea relieved and serum immunoglobulin elevated. ConclusionsCVID is the most frequent symptomatic primary immune deficiency which is related to celiac disease closely, a gluten-sensitive condition characterized by a variable degree of villous atrophy. Once diagnosed, gluten-free diet can alleviate the symptoms.

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  • One Case Report of MTX-Induced Aplastic Anemia and Literature Review

    We reported one case of MTX-induced aplastic anemia and reviewed related literature to investigate the mechanism of action of MTX, and summarize the clinical feature, diagnostic criteria, risk factor, and interventions. These were hoped to arouse the attention of clinicians and clinical pharmacists, in order to effectively prevent, diagnose, and treat MTX-induced aplastic anemia.

    Release date:2016-09-07 02:08 Export PDF Favorites Scan
  • Fungal pulmonary embolism: two cases report and literature review

    Objective To investigate the clinical characteristics and diagnosis and treatment of fungal pulmonary embolism, and to improve the understanding of this disease. Methods The diagnosis and treatment of two patients with fungal main pulmonary embolism in the First Affiliated Hospital of Guangzhou Medical University were summarized and analyzed. Literatures were retrieved from Wanfang database, China national knowledge internet database and Pubmed database with search terms of “pulmonary embolism AND mucor”, “pulmonary embolism AND aspergillus”, “pulmonary embolism AND fungi”, “pulmonary embolism AND Candida”, “pulmonary embolism AND cryptococcus”. Results Case 1, a 53-year-old female was referred, with cough, high fever, breathlessness for 2 years, chest pain for 1 year. The patient had rheumatoid arthritis and systemic lupus erythematosus history with long term prednisone treatment. Finally, the patient was diagnosed main pulmonary artery embolism (aspergillus) and disseminated aspergillosis. Although treatment with voriconazole, amphotericin B, and caspofungin were given for more than 1 year, the patient died with uncontrolled aspergillus infection. Case 2, a 67-year-old female was referred with cough, chest distress, chest pain for 8 months, breathlessness for 6 months. The patient had a history of chronic viral hepatitis C. Finally the patient was diagnosed as main pulmonary artery embolism and pulmonary valve endocarditis (aspergillus, mucor). The patient underwent pulmonary artery lesion resection and tricuspid valvuloplasty (DeVega method). After surgery, the patient was delivered with amphotericin B and posaconazole for 3 months. During the follow-up period of 1 year, the patient recovered almost totally without relapse signs. A total of 42 cases of fungal pulmonary embolism from 1980 to 2021 were retrieved (including 2 cases in this article), and 6 of these cases were main pulmonary artery embolism. Of all the cases, the median age was 49 years and 22 (54.3%) were males. 20 cases were immunocompromised. The infection pathogens included: Aspergillus (21, 50%), Candida (11, 26.2%), Mucor (7, 16.7%), and Aspergillus combined with Mucor (1, 2.5%), Coccidioides spp (1, 2.5%), and Cryptococcus (1, 2.5%). Fifteen cases were complicated with infection other than cardiopulmonary. Twenty-two cases were treated with surgery combined with antifungal medicine, and 9 cases with antifungal medicine alone. Twenty-two cases were dead and the overall mortality rate was 52.4%. There were statistically significant differences in the effects of fungal species, dissemination of other organs other than the heart and lung, and surgical treatment on the survival rate. The survival rate of different fungal species was significantly different. Dissemination to organs other than the heart and lungs reduces survival, whereas surgical treatment improves survival. Conclusions Fungal pulmonary embolism, a disease with high mortality, rarely involves the main pulmonary artery. The possibility of fungal pulmonary embolism should be considered when the cause of pulmonary thrombosis is unknown and the anticoagulant effect is poor. Although there is no unified treatment at present, early surgical combined with standard antifungal treatment may improve the prognosis of patients.

    Release date:2022-10-27 10:51 Export PDF Favorites Scan
  • 胰腺 Castleman 病 1 例报道并文献复习

    目的 总结 1 例胰腺 Castleman 病患者的临床资料,并复习以往文献,总结该病的流行病学特点及诊治体会。 方法 回顾性分析 2016 年 1 月笔者所在医院收治的 1 例胰腺 Castleman 病患者的临床资料,进行文献复习及总结。 结果 该例患者无特殊临床表现,术前行 CT 检查发现胰腺占位,行手术切除,术后病理学诊断为胰腺 Castleman 病。术后 1 个月复查CT未见肿瘤复发及转移,已获访 6 个月,患者恢复良好。经查阅文献,共检索出胰腺 Castleman 病 32 例,男 11 例,女 21 例;年龄 23~74 岁,平均年龄为 46 岁;临床表现仅为腹部疼痛 7 例,腹痛伴发热 1 例,腹痛伴面部、双下肢水肿 1 例,腹痛伴乏力 1 例,腹胀 1 例,背部疼痛 1 例,颈部淋巴结肿大 1 例,吞咽困难 1 例,发热、乏力、体质量下降 1 例,无明显临床表现 17 例;肿瘤位于胰腺头部 9 例,胰腺颈部 3 例,胰腺体、尾部 16 例,胰周 4 例;肿瘤直径最小 1.5 cm,最大 7.2 cm;病理学分型为透明血管型(hyaline vascular,HV)19 例,浆细胞型(plasma cell,PC)4 例,混合型(mixed/HV-PC,MV)4 例,未给出明确病理分型 5 例。 结论 胰腺 Castleman 病是少见的淋巴组织增生性疾病,通常无特异临床表现,影像学检查也无特异性,目前仅能通过病理组织学检查确诊。胰腺 Castleman 病的治疗以手术为主,疗效较好。

    Release date:2017-04-01 08:56 Export PDF Favorites Scan
  • Influenza A H1N1 virus infection: literature review of clinical and epidemiological features for 881 patients in China in the past thirty years

    ObjectiveTo analyze the clinical features, laboratory examination, imaging findings, treatment and outcome of influenza A H1N1 virus infection in China, so as to improve the clinicians' understanding of the disease.MethodsOne patient with influenza A H1N1 pneumonia was reported in this hospital. The databases of CNKI, VIP network and Wanfang data were systematically consulted. After removing the duplicate and deleting the incomplete literature published between January 1989 and August 2019, 62 literatures were included, involving 880 patients. Hence, 881 patients in total were included. The clinical manifestations, laboratory examination, imaging manifestations, treatment and prognosis were analyzed.ResultsThere were 477 males and 404 females, aged from 50 days to 86 years old, with an average age of (20.4 ±10.0) years. The most common clinical symptoms were fever (99.4%, 876/881), followed by cough (85.0%, 749/881), expectoration (38.1%, 336/881), sore throat (37.0%, 326/881) and dyspnea (33.7%, 297/881), asthenia and general pain (33.5%, 295/881) and so on. Laboratory examination in the leukocyte decreased in 249 patients (28.3%), neutrophil increased in 143 patients (16.2%) and leukocyte increased in 141 patients (16.0%). Myocardial injury was found in 370 patients (42.0%), liver injury in 303 patients (34.4%) and renal insufficiency in 84 patients (9.5%). The main imaging manifestations were spotted, patchy or flaky shadows (41.8%, 362/866) in varying degrees, with consolidation shadows (19.3%, 167/866), thickening of lung texture (11.3%, 98/866), ground glass shadows (4.5%, 39/866), and pleural effusion (5.5%, 48/866). The most common treatments were anti-virus, anti-infection, anti-inflammation, mechanical ventilation and symptomatic support. Comprehensive treatment resulted good effects. There were 37 deaths and the mortality rate was 4.2%. The main cause of death was respiratory failure.ConclusionsInfluenza A H1N1 virus infection is a preventable, controllable and treatable infectious disease, which is similar to the general influenza virus. After active comprehensive treatment, most of the influenza A (H1N1) can be cured and the prognosis is benign.

    Release date:2021-04-25 10:17 Export PDF Favorites Scan
  • MDT discussion of 2 cases of hepatocellular carcinoma with bile duct tumor thrombus

    Objective To discuss the clinical characteristics, radiological characteristics, diagnosis, and treatment of hepatocellular carcinoma with bile duct tumor thrombus (HCCBDTT), and to improve the level of diagnosis and treatment for it. Methods Clinical data of 2 cases of HCCBDTT admitted in March 2016 and July 2016 in our hospital were analyzed retrospectively, and the related literatures were reviewed. Results Two cases of HCCBDTT were misdiag- nosed as hilar cholangiocarcinoma before operation, and then proved to be HCCBDTT after operation. The 2 cases were both alive during the follow-up period (20 months and 13 months respectively). Conclusions HCCBDTT patients should be comprehensively analyzed basing on the clinical data for diagnosis, and avoiding misdiagnosis. Active surgical treatment can effectively improve the quality of life in HCCBDTT patients, and prolong the survival time.

    Release date:2018-05-14 04:18 Export PDF Favorites Scan
  • The Mounier-Kuhn syndrome: three cases report and literature review

    Objective To summarize the etiology and clinical features of Mounier-Kuhn syndrome (MKS) so as to enhance the acknowledgement of MKS. Methods Three cases of MKS were reported and the keywords with " Tracheobronchomegaly”, " Mounier-Kuhn syndrome” were analyzed through the mode of literature retrieval in CNKI, VIP and Pubmed databases. Results There were 214 cases around the world including 14 cases of MKS in China. With unknown etiology and non-specific clinical feature, MKS is characteristic with congenital absence of tracheal or bronchial elastic tissue. MKS is diagnosed with remarkably dilated trachea and bronchus through chest CT or bronchofibroscope, accompanied with genetic defects. The ratio of men to women is 8.5 to 1. There is no radical cure. Symptomatic treatment and surgical treatment when necessary could be available. Conclusions MKS is a rare progressive hereditary disease, irrelevant to smoking and sharing a similar cause with generalized elastolysis, which need pay much attention to the physical examination of skin or elastic tissue. The diagnosis of MKS should be based on not merely airway diameter but also the overall clinical, pathologic, and radiologic profile.

    Release date:2017-05-25 11:12 Export PDF Favorites Scan
  • 1 例具特殊影像特征甲状腺髓样癌的诊治体会并文献复习

    目的 探讨具特殊影像特征的甲状腺髓样癌(MTC)的临床诊治策略。 方法 回顾性分析笔者所在医院于 2016 年 11 月收治的 1 例 MTC 病例的临床资料和诊治经过,并进行文献复习。 结果 该例患者的颈部超声检查表现为甲状腺腺瘤征象,术前血清降钙素(Ctn)检查结果异常升高,复查 Ctn的同时行血清癌胚抗原(CEA)、细针穿刺细胞学检查(FNA)及洗脱液 Ctn 检查,结果均提示 MTC 可能。根据术前影像学检查和术中病理检查结果行甲状腺癌根治术,术后病理确诊为 MTC。 结论 超声检查下不典型征象结节往往是 MTC 误诊的主要原因,故对于尚不能排除 MTC 可能者应该考虑进一步行血清 Ctn、血清 CEA、FNA、洗脱液 Ctn 等检查以明确诊断,避免延误治疗。

    Release date:2017-06-19 11:08 Export PDF Favorites Scan
  • Small Intestine Intussusception Induced by Juvenile Polyps:A Systematic Literature Review

    目的 提高对幼年性息肉致小肠套叠的诊治水平。方法 按检索策略,检索PubMed、中国生物医学文献数据库(CBM)、中文科技期刊全文数据库(CSJD)、中国期刊全文数据库(CJFD)及CNKI数字图书馆的相关文献,并结合笔者所在医院于2011年收治的1例幼年性息肉致小肠套叠病例资料,对该病进行一系统的描述。结果 共检出相关文献65篇,按纳入及排除标准,最后纳入6篇文献。共7例患者,临床表现为腹痛、呕吐5例,便血2例,贫血3例;经超声检查诊断4例;全组均行小肠切除肠吻合术,其中1例为腹腔镜辅助手术;有1例患者共实施了3次手术,最后死于恶液质,其余患者恢复较好。结论 幼年性息肉致小肠套叠为临床罕见疾病,超声检查仍为首选诊断方法;提高医师对该病的认识,术中彻底探查肠道,必要时术中行快速冰冻切片病理学检查,有望减少息肉遗留,改善患者的预后。

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