目的 探讨结肠癌和直肠癌并发肠穿孔的外科诊治方法。方法 分析13例结直肠癌并发肠穿孔患者的临床资料。结果 13例患者中4例行肿瘤所在肠段一期切除吻合术; 4例行一期病灶切除吻合术,近端肠段行外置双管造瘘术; 2例切除肿瘤所在肠段,近端行端式结肠造瘘术,远端行封闭(Hartmann)术; 3例行单纯肠造瘘术。术后并发症发生率为46.15%(6/13),手术死亡率为15.38%(2/13)。结论 重视对结直肠癌并发肠穿孔的认识及选择合适的手术方式是减少并发症、提高疗效的重要措施。
目的 探讨腹腔镜下修补医源性结肠穿孔的可行性和手术技巧。方法 回顾性分析我院2007年 10月至2009年12月期间腹腔镜下修补医源性结肠穿孔手术6例患者的临床资料,其中诊断性肠镜检查结肠穿孔2例,治疗性肠镜结肠穿孔4例。结果 6例患者均顺利完成腹腔镜下手术, 无中转开腹。3例患者全腹腔镜下完成结肠穿孔修补,2例因破口较大在腹腔镜辅助下完成结肠穿孔修补,1例乙状结肠癌患者肠镜检查结肠穿孔后同时行腹腔镜下乙状结肠癌根治手术,术后未发生吻合口漏、残余感染等并发症。结论 腹腔镜下修补医源性结肠穿孔安全、可靠,临床效果肯定。
目的 探讨老年人自发性乙状结肠穿孔的病因、诊断及治疗方法。方法 对四川大学华西医院胃肠外科中心2009~2011年期间收治的9例自发性乙状结肠穿孔老年患者的临床资料进行回顾性分析。结果 9例患者中7例有长期便秘史,术前均诊断为“全腹膜炎、腹腔脏器穿孔”而行急诊手术。术中见穿孔位于直乙交界处6例,乙状结肠中上段3例,均在系膜对侧缘。3例行病变处肠段切除加远端封闭、近端造瘘术(Hartmann术),4例行乙状结肠部分切除吻合、横结肠双腔造瘘术,1例行穿孔修补术,1例行穿孔修补加横结肠造瘘术。8例患者治愈出院,1例患者因经济原因放弃治疗。结论 老年人自发性乙状结肠穿孔临床上较少见,其发病与解剖学因素、病理学因素密切相关,便秘等是其重要诱因。及时手术、选择适宜的手术方式以及彻底清除腹腔污染是治疗成功与否的关键。
ObjectiveTo analyze the surgical effect, postoperative complications and effects on the body inflammatory response of laparoscopic gastroduodenal perforation repair, and to further evaluate the efficacy of laparoscopic perforation repair. MethodsWe retrospectively analyzed the clinical data of 123 patients with gastroduodenal ulcer perforation treated between February 2010 and February 2015. Among the patients, 65 underwent laparoscopic gastroduodenal ulcer perforation repair (laparoscopic group), and 58 underwent routine open gastroduodenal ulcer perforation repair (open group). Then, we compared the surgical effects (average bleeding volume, ambulation time, postoperative ventilation time, postoperative hospital stay), postoperative complications (wound infection, wound dehiscence, gastroduodenal fistula, abdominal abscess, intestinal obstruction), inflammatory reaction[preoperative and 1, 3, 5-day postoperative white blood cells (WBC) count, peripheral blood procalcitonin (PCT), C-reactive protein (CRP)] between the two groups. ResultsPatients in both the two groups underwent the surgery successfully. No patients in the laparoscopic group were transferred to open surgery. Compared with the open surgery, surgical bleeding volume, ambulation time, anal exhaust time and postoperative hospital stay of the laparoscopic group were significantly different (P < 0.05). Postoperative complications rate of the laparoscopic group was significantly lower than that of the open group (P < 0.05). One and 3-day WBC, PCT and CRP after surgery increased obviously in both the two groups. The above three indicators on the fifth day after surgery were not significantly different from those before the surgery in the laparoscopic group (P > 0.05), while they were significantly different from those before the surgery in the open group (P < 0.05). ConclusionsCompared with open perforation repair, laparoscopic perforation repair surgery is superior for its better surgical effects, fewer postoperative complications and lighter inflammatory response. It is a safe, effective and minimally-invasive treatment for gastroduodenal perforation.