west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "陈娟" 33 results
  • 围生期脑卒中的研究进展及诊治现状

    围生期脑卒中是一种严重的神经系统疾病,近年来引起了临床医生的高度重视。由于该病缺乏特异性症状和体征,常漏诊和延误治疗,部分患者遗留严重的神经系统后遗症,影响患儿的生活质量。因此有必要提高对该病的认识,熟悉其病因和诊疗手段。现就围生期脑卒中的病因、相关危险因素及治疗的最新研究进展作一综述。

    Release date: Export PDF Favorites Scan
  • 早产儿初始持续气道正压通气失败的危险因素分析

    目的 分析早产儿初始持续气道正压通气(continuous positive airway pressure,CPAP)失败的相关危险因素,为早产儿选择有效的呼吸支持方式提供临床依据。 方法 选取 2014 年 1 月—12 月在新生儿科住院初始呼吸支持为 CPAP 的早产儿 152 例,对其临床资料进行回顾性研究,分析 CPAP 失败的相关危险因素。 结果 单因素分析显示出生体质量、胎膜早破、脐带异常、宫内窘迫、生后窒息、孕母妊娠期高血压、孕母妊娠期糖尿病、产前使用激素、使用 CPAP 时日龄、初始吸入氧浓度、初始氧分压这 11 项因素与 CPAP 失败的关联有统计学意义;logistic 回归分析表明低出生体质量、宫内窘迫、使用 CPAP 较晚是影响 CPAP 失败的主要危险因素。 结论 综合分析出生体质量、宫内窘迫、使用 CPAP 日龄等围生期因素是 CPAP 失败的主要预测因素。

    Release date:2017-04-19 10:17 Export PDF Favorites Scan
  • Obtaining, Identifying and Marking of the Human Umbilical Cord-derived Mesenchymal Stem Cells in Vitro

    ObjectiveTo obtain the mesenchymal stem cells (MSCs) from human umbilical cord and mark in vitro, for further transplantation therapy. MethodsThe MSC were isolated from human umbilical cord by tissue explants culture method. After subculture in vitro, the morphology of hUC-MSC was observed; the surface antigens of hUC-MSC were detected by flow cytometry; adipogenic and osteogenic differentiation were determined by specific staining; hUC-MSC labelled with Brd U were identified by immunofluorescence. ResultsMSC could be isolated successfully by tissue explants culture method. When cultured about one week, the cells climbed out from the tissue block edge, proliferated and formed colonies; the hUC-MSCs of passage 5 were detected by flow cytometry, and they highly expressed CD73, CD90 and CD105, didn't express or lowly expressed CD14, CD34, CD45, CD79a and human leukocyte antigen-DR. After two weeks of adipogenic induction, they were positive in oil red O staining, and after three weeks of osteogenic induction, red precipitate could be seen by alizarin red staining, and the red fluorescence of the hUC-MSC labelled with Brd U could be detected by immunofluorescence detection. ConclusionThe cells can be isolated from human umbilical cord by tissue explants culture method, with the characteristics of hUC-MSCs and can be labeled successfully in vitro, so it can be used for the research in the field of cell transplantation.

    Release date: Export PDF Favorites Scan
  • 电针刺激厌恶疗法合并心理疗法治疗酒精依赖患者的康复护理模式

    目的探讨酒精依赖患者电针刺激厌恶疗法合并心理治疗的康复护理模式的疗效。 方法对2011年10月-2012年4月收治的60例住院酒精依赖患者,在常规药物治疗的基础上应用电针刺激厌恶疗法合并心理疗法进行治疗,并采用饮酒渴求程度量表及汉密尔顿焦虑量表对治疗前后患者的焦虑症状及治疗效果进行评价。 结果60例患者治疗后饮酒渴求程度量表及汉密尔顿焦虑量表评分均低于治疗前(P<0.001);随访3个月时复饮13例,复饮率为21.67%,6个月时复饮17例,复饮率为28.33%。 结论康复护理模式能有效提高酒精依赖患者接受电针刺激厌恶疗法的依从性,治疗中给予的心理护理、疼痛护理、暗示治疗及健康指导,能帮助患者建立健康的生活方式,促进康复并防止复饮。

    Release date: Export PDF Favorites Scan
  • The Study about the Output of SCI Dissertation of PhD Postgraduate in Its Relation with Tutor in An Affiliated Teaching Hospital

    摘要:目的: 从医学博士研究生SCI论文产出情况分析导师队伍建设中的问题,为改革医学博士研究生教育提供依据。 方法 :以某临床附属医院2003年~2008年毕业的医学科学学位博士研究生发表SCI论文情况及导师情况为研究对象,进行定量与定性分析。 结果 :导师所属学科水平、科研经费、国外教育背景及科研管理工作等方面均对博士生SCI论文的产出有影响。 结论 :增强导师队伍的科研能力和管理责任是完善导师队伍建设的方向。Abstract: Objective: To found the questions of tutor construction on the basis of SCI dissertation of PhD postgraduate and provide the evidence for transforming the medical doctor education.〖WTHZ〗Methods :Quantitative and qualitative analysis was done on the basis of the condition of the tutor and the publication of SCI paper of PhD postgraduates from 2003 to 2008 in second clinical Medical college of Beijing University. Results : The factors affecting the publication of SCI paper of PhD postgraduate included academic level、research fund、abroad ducation background and reseach management of the teacher. Conclusion : The reseach capability and management duty of the tutor must be strengthened to improve the construction of the tutor.

    Release date:2016-09-08 10:12 Export PDF Favorites Scan
  • Clinical Analysis of 160 Cases of Initial Continuous Positive Airway Pressure in Premature Infants

    ObjectiveTo analyze the application and efficacy of continuous positive airway pressure (CPAP) as an initial support measure for respiratory diseases in premature infants. MethodsWe retrospectively studied the clinical data of 160 premature infants hospitalized in the Neonatal Intensive Care Unit from January to December 2014. These infants accepted CPAP as the initial respiratory support. ResultsThe average birth weight and the average gestational age of the 160 premature infants were (1 581±440) g and (31.6±1.9) weeks, respectively. The main diagnosis of the primary diseases in these infants included neonatal pneumonia (81.3%), neonatal respiratory distress syndrome (57.5%), neonatal apnea (53.8%) and neonatal asphyxia (22.5%). The CPAP success rate in those infants whose birth weight was less than 1 000 g was significantly lower than those whose birth weight was equal or greater than 1 000 g (χ2=4.882, P=0.027). The perinatal period analysis showed that premature rupture of membranes, intrauterine fetal distress and maternal pregnancy complications were factors correlating with the effect of CPAP. CPAP treatment analysis showed that early application of CPAP within 24 hours after birth had a success rate of 82.4% (108/131), and initial inhaled oxygen concentration and oxygen pressure were the primary factors affecting CPAP efficacy. ConclusionApplication of CPAP is effective in respiratory support for premature infants and has a high success rate. Early application can reduce the use of mechanical ventilation and intubation. Regulating appropriate parameters helps raise the efficacy of CPAP therapy. Clinically, the standardized application of CPAP and monitoring the failure of CPAP are important for the improvement of the treatment efficacy.

    Release date:2016-11-23 05:46 Export PDF Favorites Scan
  • 爪形肋骨接骨板在多发性肋骨骨折内固定手术中的应用

    Release date:2016-08-30 05:50 Export PDF Favorites Scan
  • Clinical Analysis on Neonatal Respiratory Failure

    ObjectiveTo explore the incidence, treatment and prognosis of neonatal respiratory failure (NRF). MethodsThe clinical data of 421 neonates with NRF treated between January 2011 and December 2013 were retrospectively analyzed. ResultsThe incidence and the mortality of NRF was 4.8% and 14.5%, respectively. The main primary disease of NRF was neonatal respiratory distress syndrome (36.1%) and aspiration pneumonia (29.0%). Mechanical ventilation was the main treatment for NRF (77.2%). Premature (χ2=12.216, P<0.001), low birth weight (χ2=8.932, P=0.003) and the neonatal asphyxia (χ2=6.199, P=0.013) were closely related to the prognosis of NRF, which were the risk factors of the death of NRF. ConclusionNRF is a disease with high incidence and high mortality; make effective prevention and treatment measures are important to improve the success rate of therapy for NRF.

    Release date: Export PDF Favorites Scan
  • 25例新生儿气胸临床分析

    Release date:2016-09-08 10:14 Export PDF Favorites Scan
  • Clinical Characteristics of Infantile Acute Leukemia

    目的 探讨婴儿急性白血病(IAL)的临床与实验室检查特征。 方法 对1999年12月-2011年6月收治的15例婴儿急性白血病的临床资料进行总结与分析。 结果 其中急性淋巴细胞白血病(ALL)6例,急性髓系白血病(AML)8例,分类不明1例,其中以M4(4例)、M5(3例)为主。临床表现多样,髓外浸润明显。1例细胞形态学与免疫分型有差异,1例合并染色体异常。放弃治疗者11例,死亡2例,正规治疗的2例于诱导缓解后获完全缓解。 结论 IAL预后差,需完善相关检查并不断总结临床资料以提高IAL治愈率。

    Release date:2016-09-08 09:12 Export PDF Favorites Scan
4 pages Previous 1 2 3 4 Next

Format

Content