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Curative Effect Observation on Treatment of Lower Limb Thrombophlebitis ofSuperficial Phlebitis with Trivex Cutting System

目的　探讨Trivex旋切术治疗下肢血栓性浅表静脉炎的临床疗效。方法　回顾性分析67例下肢血栓性浅表静脉炎病例的临床资料。患者术前给予丹参治疗、下肢静脉造影等术前准备； 然后行大隐静脉主干内膜剥脱、用Trivex旋切系统剖吸曲张静脉和静脉丛内的血栓； 术后给予低分子肝素抗凝、早期下床活动等处理。结果 全部患者的手术均顺利，术中及术后无肺栓塞发生。术后2例切口Ⅱ期愈合， 65例切口Ⅰ期愈合。所有病例术后3d均出院，住院时间（5±1） d。15例术后患肢有瘀斑者随访2周均消失； 7例出现内踝部麻木感，随访6个月消失； 本组患者均获随访6个月，未见复发者。结论　下肢血栓性静脉炎早期行以Trivex旋切术为主的综合治疗，其临床疗效好、住院时间短、创伤小及美容效果好，并可有效防止病情反复、深静脉血栓及肺栓塞的发生，是治疗下肢血栓性静脉炎的有效手段。

海绵窦血栓静脉炎

报道6例海绵窦血栓静脉炎，5例经治疗眼症状及全身症状消失，1例死亡。感染为首先要原因，多在1～3个月发病，可能与气候寒冷易感冒有关。因海绵窦解剖特点，体征较早表现于眼部，幼年者易患，故有感染性疾病者应警惕发生本病，视力损害严重，应特别重视。 （中华眼底病杂志，1993，9：106-107）

留置时间与静脉留置针所致静脉炎的相关性研究

目的：探讨留置时间与静脉留置针所致静脉炎的相关性，寻求安全的使用方法。方法：运用静脉炎调查分析量表，对608例患者使用静脉留置针的情况进行调查分析。结果：共有43例患者发生静脉炎，留置时间＞7天组及6～7天组，与其他各组间比较P＜0.05，差异有经计学意义；而其余三组间比较P＞0.05，没有显著性差异。留置时间与静脉炎发生率的相关系数为0.9315。结论：留置时间与静脉留置针所致静脉炎有正相关性，留置时间超过5天后，静脉炎的发生率即显著升高。

Neodoxy of Superficial Thrombophlebitis

Association of human leucocyte antigen-DRB and -DQB alleles with Eales′ disease

Objective To analyze the association of human leucocyte antigen (HLA)-DRB and -DQB alleles with Ealesprime; disease, and to investigate the potential immunogenetics mechanism of Ealesprime; disease. Methods Gene loci of HLA-DRB and -DQB1 alleles were detected by polymerase chain reaction-sequence specific primer (PCR-SSP) in 27 Han-nationality patients with Ealesprime; disease in Northern China and 30 age and sex-matched normal persons as control, then statistics package for social science (SPSS) for Windows ver 13.0 software was used to analyze the distribution features of frequency of HLA-DRB and -DQB1 alleles in the two groups. Results Compared with the control group, the frequency of HLA-DRB104 allele increased obviously in the patients with Ealesprime; disease［odds ratio (OR)=3.20 ，OR 95% confidence interval（CI）=1.00-10.21, and P=0.047］. Simultaneously, no statistically significant difference of the distribution of any other DRB or DQB1 allele between the two groups was found (Pgt;0.05). Conclusions In hannationality people in Northern China, DRB104 is positively associated with Ealesprime; disease, suggesting that DRB104 may confer a major influence on Ealesprime; disease. Turbulence of immune function begotten by infect-agents attack may occur in the individuals with Ealesprime; disease due to the specific hereditary diathesis of HLA, which may cause the occurrence and development of Eales disease. (Chin J Ocul Fundus Dis, 2006, 22: 90-93)

康惠尔水胶体透明贴用于肿瘤患者PICC置管术后的护理研究

目的:观察康惠尔水胶体透明贴用于PICC置管术后静脉炎预防的效果。方法:将126例PICC置管的患者随机分为实验组61例,对照组65例。实验组从置管当日开始使用康惠尔水胶体透明贴,对照组从置管当日用3M透明敷贴,观察两组静脉炎的发生率。结果:实验组61例患者无一例发生静脉炎,对照组65例患者有4例发生静脉炎,统计学上有显著性差异(P＜0.05)。结论:康惠尔水胶体透明贴在预防静脉炎方面有明显的效果,PICC置管时首选贵要静脉可明显降低静脉炎的发生率。

弹力绷带在经外周静脉置入中心静脉导管置管中的固定作用及效果

目的　讨论弹力绷带在经外周静脉置入中心静脉导管（PICC）置管中的固定作用及对减少局部渗血、渗液和预防机械性静脉炎的效果。 方法　选择2011年6月－2012年3月在某三甲医院重症医学科（ICU）行PICC置管的100例患者，按穿刺时间先后顺序单号纳入对照组，双号归于试验组,每组各50例。对照组置管后在穿刺局部放置8层无菌方纱，外用 10 cm×12 cm的透明敷料外固定；试验组在对照组的基础上增加弹力绷带固定,分别观察两组患者置管后24、72 h局部渗血、渗液、机械性静脉炎的发生情况。 结果　在24、72 h两个时间点，试验组渗血、渗液发生率少于对照组（χ2=4.57，P＜0.05）；静脉炎发生率在24 h时低于对照组（χ2=4.00，P＜0.05），但在72 h差异无统计学意义。 结论　PICC置管患者使用弹力绷带固定不仅可防止穿刺点渗血渗液，减少机械性静脉炎的发生，而且可减轻护士工作量，值得临床推广使用。

LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN THE VITREOUS OF PATIENTS WITH RETINAL VEIN OCCLUSION AND EALES' DISEASE

PURPOSE:To investigate the content of vascular endothelial growth factor (VEGF)in vitreous of patients with retinal vascula'r proliferative diseases. METHODS:The concentration of VEGF in undiluted vitreous samples from patients with retina vein occlusion (RVO) (n=7),Eales disease (n=7)and controls (n=7) was measured by enzyme linked immunosorbent assay (EL1SA). RESULTS:The levels of vitreous VEGF were significantly higher 13 folds in patients with RVO(4.67plusmn;3.38)ng/ml and 5 folds in patients with Eales disease(1.79plusmn;0.44)ng/ml than in controls (0.35plusmn;0.15)ng/ml separately(P＜0. 01). CONCLUSIONS:VEGF might play a part in mediating the neovascularization of retinal vascular diseases. （Chin J Ocul Fundus Dis,1997,13:171-173）

特定电磁波照射对预防老年患者经外周静脉置入中心静脉导管后机械性静脉炎的效果

目的　观察使用特定电磁波（TDP）照射对预防老年患者经外周静脉置入中心静脉导管（PICC）后机械性静脉炎的效果。 方法　2010年1月－12月将120例行PICC的肿瘤科老年患者根据登记号分为观察组和对照组，每组60例。对照组进行PICC常规护理；观察组在PICC常规护理基础上于置管24 h后加用TDP治疗，2次/d，20～30 min/次，连续使用7 d。观察两组机械性静脉炎的发生情况。 结果　观察组机械性静脉炎发生率8.33%，对照组23.33%，差异有统计学意义（P＜0.001）。 结论　应用TDP能有效预防和减少PICC所致机械性静脉炎的发生。

Clinic Effect of Comfeel Transparent Paste on Prevention of Phlebitis with Breast Cancer Who Firstly Used Chemotherapy Treatment after Surgery

目的:观察康惠尔透明贴防治表阿霉素(E--ADM)联合用药致静脉炎的临床效果。方法:将160名第1次大剂量(100mg／m2)静脉滴注表阿霉素的乳腺癌术后患者按床号的单双数随机分为对照组和实验组各80例,静脉穿刺处对照组使用3M透明贴,实验组使用康惠尔透明贴,观察两组患者静脉炎发生率及严重程度。结果:对照组发生静脉炎31例,实验组发生静脉炎9例。两组经秩和检验,W=6.638 P=0.0353。 结论:使用康惠尔透明贴能有效预防表阿霉素联合用药所致的静脉炎,值得临床推广应用。