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find Keyword "Serous maculopathy due to aspecific choroidopathy" 1 results
  • Research progress of stellate multiform amelanotic choroidopathy

    Stellate multiform amelanotic choroidopathy (SMACH) is a rare choroidal disease that can cause persistent subretinal fluid (SRF). It is more common in young individuals, with a similar male-to-female ratio, it is most often unilateral, and its clinical manifestations are diverse. The pathogenesis of SMACH is not well understood, but it may be a form of congenital choroidal dysplasia. The progressive impact of the lesion on the choroidal capillaries and the retinal pigment epithelium may be the cause of SRF. Its characteristic multimodal imaging changes include optical coherence tomography showing hyperreflective fibrous-like changes located in the inner choroidal stroma. Typical finger-like projections arranged in a stellate configuration are best seen on near-infrared imaging, indocyanine green angiography, and en face optical coherence tomography. The lesion is stable, with no progressive changes, and is unresponsive to treatment. Clinicians have limited knowledge about SMACH, which can lead to patients undergoing unnecessary or inappropriate treatments. Therefore, it is necessary to understand and recognize SMACH early in clinical practice.

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