目的 通过分析影响四川地区慢性乙型肝炎患者抗病毒治疗依从性的因素，探讨提高患者治疗依从性的策略。 方法 选择2011年4月－2012年4月在四川大学华西医院接受核苷（酸）类似物抗病毒治疗的324例慢性乙型肝炎患者作为研究对象。采用问卷调查的方法，对患者一般情况、心理状态、文化程度、经济情况、疾病认知情况、抗病毒疗效、服药持续性等相关因素进行分析，评估这些因素对患者治疗依从性的影响。 结果 324例患者中能够完全遵照医嘱者78例（24.07%），不能完全依从者246例（75.93%）。心理状态良好者132例（40.74%），其中依从性良好者54例；心理负担较重者192例（59.26%），其中依从性良好者24例。初中及以上学历204例（62.96%），依从性良好者72例；初中以下学历者120例（37.04%），依从性良好者仅6例。不同心理状态、文化程度的患者依从率差异有统计学意义。患者经济状况、年龄差异对于依从性也有一定影响。 结论 慢性乙型肝炎患者对抗病毒治疗的依从性与心理状态、文化程度者及经济状况密切相关。改善患者医疗费用偿付能力，对患者进行疾病认知教育以及减少社会歧视等措施有助于提高患者治疗依从性。
Objective To assess the current status of medical waste management and classification disposal in hospitals across Hubei Province, providing a scientific basis for optimizing medical waste disposal strategies and promoting waste minimization, harmless treatment, and resource utilization. Methods A random sample survey was conducted on medical and health institutions in Hubei Province between January 8 and January 17, 2025. The self-made survey questionnaire was used to survey and analyze the medical waste management and classification disposal in medical and health institutions. Results A total of 257 medical and health institutions were surveyed. Among them, there were 93 tertiary hospitals (36.19%), 75 secondary hospitals (29.18%), 77 primary hospitals (29.96%), and 12 non-graded medical institutions (4.67%). The overall compliance rate for medical waste management and training exceeded 90%. In terms of medical waste supervision sections, compliance rates in primary hospitals and non-graded hospitals were 77.92% (60/77) and 58.33% (7/12), respectively. The compliance rate for medical waste classification and disposal was above 90%, with a 100% (221/221) compliance rate for the disposal of placentas from normal deliveries. However, the standardized disposal rates for “fetal tissues from pregnancies under 16 weeks or weighing less than 500 grams”, “amputation and other human tissues (or organs)” and “dead fetus” were 81.45% (180/221), 44.65% (96/215), and 79.64% (176/221), respectively. Additionally, 87.16% (224/257) of healthcare institutions classified single-use soft infusion bottles (bags) as recyclable waste, but significant variations were observed in the disposal of uncontaminated waste (e.g., empty disinfectant bottles, empty dialysis fluid barrels, oxygen humidifier bottles, and orthopedic casting materials). Furthermore, 99.61% (256/257) of hospitals provided protective equipment for medical waste handlers, 91.83% (236/257) conducted regular health examination to them, and 97.28% (250/257) had established needle stab reporting systems and related training programs. Conclusions Medical waste management and classification in hospitals across Hubei Province are largely standardized. However, the certain categories of medical waste still require stricter regulation and oversight.